Articles with the topic: disease-modifying

Advances on many fronts in the battle against the protein that causes Huntington's disease

Advances on many fronts in the battle against the protein that causes Huntington's disease

This fall sees exciting announcements from a number of companies focused on novel Huntingtin Lowering technologies, including Wave, PTC and Voyager

Dr Jeff CarrollDecember 04, 2018

Has a "wonder drug" for dementia been discovered? (Spoiler alert: no.)

Has a "wonder drug" for dementia been discovered? (Spoiler alert: no.)

Media reports of a wonder drug for neurodegenerative diseases like Huntington's disease are overhyped

Dr Michael FlowerMay 07, 2017

Important advances in next generation genome editing tools for Huntington's Disease

Important advances in next generation genome editing tools for Huntington's Disease

Work with genome editing techniques (zinc fingers and CRISPR) brings these tools closer to use in HD clinical trials

Mr. Shawn MinnigOctober 31, 2016

Liftoff: First humans treated with gene silencing drugs for HD!

Liftoff: First humans treated with gene silencing drugs for HD!

Major Announcement: First HD patients treated with gene silencing drugs

Dr Jeff CarrollOctober 22, 2015

Measuring harmful huntingtin protein in the brain’s bath water

Measuring harmful huntingtin protein in the brain’s bath water

How will we know whether HD-lowering treatments are working? New advancements in the detection of mutant huntingtin.

Dr Michael OrthMay 18, 2015

Could HD be caused by amino acid deficiency?

Could HD be caused by amino acid deficiency?

Does a specific amino acid deficiency contribute to the development of HD?

Dr Jeff CarrollApril 21, 2014

Does high-dose creatine "slow the onset" of Huntington's Disease?

Does high-dose creatine "slow the onset" of Huntington's Disease?

A new study claims that high-dose creatine "slows the onset of Huntington Disease". How much hope and how much hype?

Dr Jeff CarrollFebruary 11, 2014

Prana Biotech publishes Huntington's disease animal model data for PBT2

Prana Biotech publishes Huntington's disease animal model data for PBT2

Prana Biotechnology has released data demonstrating their drug, PBT2, is effective in animal models of HD

Dr Jeff CarrollJanuary 14, 2013

ASO gene silencing reaches further, lasts longer

ASO gene silencing reaches further, lasts longer

Silencing the Huntingtin gene using ASO drugs reaches further, lasts longer and is safe. Human trial soon?

Dr Nayana LahiriJune 21, 2012