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14 changes for a healthier brain

14 changes for a healthier brain

In 2019, there were ~57 million people living with dementia. By 2050, that number is expected to climb to 153 million. Changes in the 14 factors highlighted here can improve brain health and be applied to Huntington’s disease.

Dr Sarah HernandezSeptember 30, 2024

Highlighting a link between brain disorders on Ataxia Awareness Day

Highlighting a link between brain disorders on Ataxia Awareness Day

September 25th is Ataxia Awareness Day, so HDBuzz is highlighting the connections between HD and Ataxia research. Learn about how these fields have historically grown in parallel and informed one another.

Dr Leora FoxSeptember 25, 2024

Hope vs. hype: seeking truth in recent Prilenia headlines

Hope vs. hype: seeking truth in recent Prilenia headlines

Although pridopidine has suffered four negative trials for HD, the message from Prilenia continues to be positive. What is hope and what is hype in this sixteen-year quest for regulatory approval?

Dr Sarah HernandezSeptember 10, 2024

Mini brains grown in a dish shed light on Huntington’s disease and how we might treat it

Mini brains grown in a dish shed light on Huntington’s disease and how we might treat it

Exciting new findings using 3D human lab-grown mini brains inform ongoing HTT-lowering trials and suggest that stem cell transplants for HD may improve cell-to-cell communication and reduce disease features.

Dr Sarah HernandezAugust 23, 2024

Buckle in: Gene therapy AMT-130 appears to slow down signs of Huntington’s disease in Phase I/II clinical trial

Buckle in: Gene therapy AMT-130 appears to slow down signs of Huntington’s disease in Phase I/II clinical trial

More good news for the HD community from uniQure, whose one-and-done gene therapy appears safe and shows hints of slowing down signs and symptoms of the disease

Dr Rachel HardingAugust 16, 2024

Steady progress from uniQure - promising data to end the year

Steady progress from uniQure - promising data to end the year

uniQure ushered in the end of the year by releasing some promising data from their huntingtin-lowering gene therapy trials

Dr Leora FoxAugust 16, 2024

Hereditary Disease Foundation (HDF) conference 2024 – Day 4

Hereditary Disease Foundation (HDF) conference 2024 – Day 4

Read our live tweet compilation from clinical trials and scientific research on Huntington’s disease from Day 4 of the 2024 HDF Milton Wexler Biennial Symposium #HD2024

Dr Sarah Hernandez and Dr Rachel HardingAugust 13, 2024

Hereditary Disease Foundation (HDF) conference 2024 – Day 3

Hereditary Disease Foundation (HDF) conference 2024 – Day 3

Read our live tweet compilation from clinical trials and scientific research on Huntington’s disease from Day 3 of the 2024 HDF Milton Wexler Biennial Symposium #HDF2024

Dr Rachel Harding and Dr Sarah HernandezAugust 12, 2024

Hereditary Disease Foundation (HDF) conference 2024 – Day 2

Hereditary Disease Foundation (HDF) conference 2024 – Day 2

Read updates from clinical trials and scientific research on Huntington’s disease from Day 2 of the 2024 HDF Milton Wexler Biennial Symposium #HDF2024

Dr Tamara Maiuri, Dr Sarah Hernandez, and Dr Rachel HardingAugust 10, 2024

Hereditary Disease Foundation (HDF) conference 2024 – Day 1

Hereditary Disease Foundation (HDF) conference 2024 – Day 1

Read updates from clinical trials and scientific research on Huntington’s disease from Day 1 of the 2024 HDF Milton Wexler Biennial Symposium #HDF2024

Dr Rachel Harding, Dr Tamara Maiuri, and Dr Sarah HernandezAugust 09, 2024

Blue skies for Skyhawk: Positive news from Phase 1 trial for SKY-0515

Blue skies for Skyhawk: Positive news from Phase 1 trial for SKY-0515

There’s more good news in the forecast in the Huntington’s disease therapeutic space as we receive positive results from Skyhawk Therapeutics about their small molecule SKY-0515 that lowers huntingtin and targets somatic expansion.

Dr Sarah HernandezJuly 11, 2024

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