Latest news

Roche announces details of its 'pivotal' huntingtin-lowering study

Roche announces details of its 'pivotal' huntingtin-lowering study

The GENERATION-HD1 trial will test whether RG6042 – formerly Ionis-HTTRx – slows the progression of Huntington's disease

Dr Jeff CarrollSeptember 17, 2018

Disappointing news from LEGATO-HD trial of laquinimod in Huntington's disease

Disappointing news from LEGATO-HD trial of laquinimod in Huntington's disease

The LEGATO-HD trial of laquinimod did not slow progression of Huntington's disease. Here's the lowdown.

Dr Jeff CarrollAugust 02, 2018

HDBuzz Enrolls in Enroll-HD

HDBuzz Enrolls in Enroll-HD

As promised, HDBuzz's Jeff Carroll finally signed up for the Enroll-HD study. Learn more about this important global HD "observational study" here.

Dr Jeff CarrollJuly 31, 2018

First Dolly, now Piglet; a new Huntington’s disease pig knock-in model confirmed

First Dolly, now Piglet; a new Huntington’s disease pig knock-in model confirmed

For the first time in HD research, an animal model has been created in pigs using 2 cutting edge DNA editing t

Caroline CaseyJuly 10, 2018

New collaboration seeks to speed Huntington's disease drug licensing

New collaboration seeks to speed Huntington's disease drug licensing

Critical Path Institute launches new initiative to get HD drugs licensed as quickly as possible

Dr Jeff CarrollMay 10, 2018

HDSA’s Q&A on the latest huntingtin-lowering update from Ionis and Roche

HDSA’s Q&A on the latest huntingtin-lowering update from Ionis and Roche

Our friends at @hdsa have produced this really good Q&A document about the latest huntingtin-lowering news.

Leora FoxApril 26, 2018

Exciting Experiments in "Open Science" by Huntington's Researchers

Exciting Experiments in "Open Science" by Huntington's Researchers

Brave scientists open their notebooks to help drive HD research at the risk of getting "scooped".

Anna Marie YannyApril 20, 2018

The structure of the protein that causes Huntington's disease, revealed

The structure of the protein that causes Huntington's disease, revealed

Huntingtin protein's structure is now clear thanks to cryo-electron microscopy. This is kind of a big deal

Caroline CaseyApril 03, 2018

Huntington's disease therapeutics conference 2018 - day 3

Huntington's disease therapeutics conference 2018 - day 3

Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein - and lowering it

Dr Jeff CarrollMarch 02, 2018

Huntington's disease therapeutics conference 2018 - day 2

Huntington's disease therapeutics conference 2018 - day 2

DNA takes centre stage for day 2 of the Huntington's Disease Therapeutics Conference in Palm Springs

Dr Jeff CarrollMarch 01, 2018

Huntington's disease therapeutics conference 2018 - day 1

Huntington's disease therapeutics conference 2018 - day 1

Our daily roundup of the science presented at the 2018 HD Therapeutics Conference in Palm Springs

Dr Ed WildFebruary 28, 2018