Articles with the topic: disease-modifying

CHDI Report: Day 1

CHDI Report: Day 1

Day 1 of CHDI’s HD therapeutics conference: exploring abnormal brain connections and silencing the HD gene

Dr Jeff CarrollFebruary 08, 2011

Anti-nausea drug helps cells with the HD mutation stay healthy in a surprising way

Anti-nausea drug helps cells with the HD mutation stay healthy in a surprising way

Anti-nausea drug meclizine protects cells with the HD mutation from death by reducing cellular energy production

Dr Jeff CarrollFebruary 04, 2011

Memantine in HD: dose is everything

Memantine in HD: dose is everything

Memantine, a drug already used in Alzheimer’s disease, might help in HD, but a mouse study shows dose is everything.

Dr Jeff CarrollJanuary 15, 2011

Dimebon: disappointing in Alzheimer’s but might work in HD

Dimebon: disappointing in Alzheimer’s but might work in HD

Dimebon – disappointing results in an Alzheimer’s disease trial, but hope remains for HD.

Dr Jeff CarrollDecember 23, 2010

Minocycline: the end of the road?

Minocycline: the end of the road?

DOMINO clinical trial result: minocycline doesn’t slow down HD and shouldn’t be studied in larger trials.

Professor Ed WildNovember 10, 2010