Does a specific amino acid deficiency contribute to the development of HD?
A new study claims that high-dose creatine "slows the onset of Huntington Disease". How much hope and how much hype?
Prana Biotechnology has released data demonstrating their drug, PBT2, is effective in animal models of HD
Silencing the Huntingtin gene using ASO drugs reaches further, lasts longer and is safe. Human trial soon?
2 bits of good news for RNAi gene silencing in HD: it's safe over six months, and a way to treat bigger brain areas
Work from multiple labs suggests activating a protein called SIRT1 might help HD, but the picture is still confusing
Bone marrow transplant protects HD mice from some symptoms, suggesting the immune system may be an important target
Melatonin delays disease onset and extends survival in Huntington's disease mice – could it do the same for patients?
HDAC inhibitors explained, plus how new HDAC-related Huntington's disease research might help us find biomarkers