Articles with the topic: disease-modifying

Re-routing the huntingtin protein inside cells

Re-routing the huntingtin protein inside cells

Canadian team decodes the tags that re-route the huntingtin protein within cells, helping explain how it becomes toxi

Dr Jeff CarrollJune 26, 2011

KMO inhibitor drug improves lifespan of Huntington's disease mice

KMO inhibitor drug improves lifespan of Huntington's disease mice

Positive results from tests of a new 'KMO inhibiting' drug in Huntington's disease mice

Dr Ed WildJune 02, 2011

Gene silencing for HD: the story so far

Gene silencing for HD: the story so far

Is gene silencing as exciting as it sounds for HD, and what might the future hold?

Dr Ed WildMarch 22, 2011

Interview: Graeme Bilbe, Global Head for Neuroscience at Novartis

Interview: Graeme Bilbe, Global Head for Neuroscience at Novartis

HDBuzz interviews Graeme Bilbe, Global Head for Neuroscience at pharmaceutical giant Novartis, about their HD researc

Dr Ed WildMarch 14, 2011

CHDI Report: Day 3

CHDI Report: Day 3

Day 3 of CHDI’s HD therapeutics conference: growth factors and CHDI’s advanced therapies

Dr Jeff CarrollFebruary 10, 2011

CHDI Report: Day 2

CHDI Report: Day 2

Day 2 of CHDI’s HD therapeutics conference: figuring out energy problems in HD

Dr Ed WildFebruary 09, 2011

CHDI Report: Day 1

CHDI Report: Day 1

Day 1 of CHDI’s HD therapeutics conference: exploring abnormal brain connections and silencing the HD gene

Dr Jeff CarrollFebruary 08, 2011

Anti-nausea drug helps cells with the HD mutation stay healthy in a surprising way

Anti-nausea drug helps cells with the HD mutation stay healthy in a surprising way

Anti-nausea drug meclizine protects cells with the HD mutation from death by reducing cellular energy production

Dr Jeff CarrollFebruary 04, 2011

Memantine in HD: dose is everything

Memantine in HD: dose is everything

Memantine, a drug already used in Alzheimer’s disease, might help in HD, but a mouse study shows dose is everything.

Dr Jeff CarrollJanuary 15, 2011