Sheep can help us to identify HD biomarkers and recognize metabolic changes that occur before symptoms develop.
Work with genome editing techniques (zinc fingers and CRISPR) brings these tools closer to use in HD clinical trials
A surprising new mouse study suggests the mutant HD gene may do some of its damage during embryonic development
Researchers design a virus to more effectively deliver gene-silencing drugs throughout the brain.
An existing drug could give a boost to HD brain cells – but it may need more testing before it’s back in the clinic
Researchers use a new technique in an HD mouse to uncover a gene, Gpx6, that is protective to vulnerable neurons.
New mouse model gives insights into Huntington's disease
HD causes the normally helpful protein "ATM" to get a little overzealous. Now we can look for drugs to settle it down
HD drug changes DNA folding across generations