Articles with the topic: animal-model

HD mice provide a useful failure

HD mice provide a useful failure

Can drug trials that fail be helpful? A HD mouse study provides solid evidence of an approach that doesn't help HD

Dr Jeff CarrollJuly 22, 2014

Illuminating the progression of Huntington’s disease

Illuminating the progression of Huntington’s disease

Researchers have used mice with glowing brain cells to decipher the first steps of neurodegeneration

Dr Tamara MaiuriJune 25, 2014

The brain in Huntington's disease: greater than the sum of its parts?

The brain in Huntington's disease: greater than the sum of its parts?

An important new study asks the question: what parts of the brain might need most help in HD?

Dr Jeff CarrollMay 19, 2014

Could HD be caused by amino acid deficiency?

Could HD be caused by amino acid deficiency?

Does a specific amino acid deficiency contribute to the development of HD?

Dr Jeff CarrollApril 21, 2014

Is a new Huntington’s Disease drug study on the right Trk?

Is a new Huntington’s Disease drug study on the right Trk?

A recent HD animal study reveals that a small molecule drug could be an effective “Trk” to target for HD therapeutics

Joseph OchabaJanuary 02, 2014

DNA shutdown proteins in Huntington's disease:  More than meets the eye

DNA shutdown proteins in Huntington's disease: More than meets the eye

Blocking HDAC4 improves Huntington's disease-related problems in cells and mice - but in a surprising way

Melissa ChristiansonDecember 16, 2013

What the 'big neurodegeneration breakthrough' means for Huntington's disease

What the 'big neurodegeneration breakthrough' means for Huntington's disease

Are recent findings in mice injected with 'prions' as important for Huntington's disease as widely reported?

Eric MinikelOctober 15, 2013

Could muscle problems help explain movements in Huntington’s Disease patients?

Could muscle problems help explain movements in Huntington’s Disease patients?

Proper contraction of muscles is crucial for coordination; errors in this process might help explain movements in HD

Dr Kurt JensenSeptember 06, 2013

Can sad mice help treat Huntington's disease?

Can sad mice help treat Huntington's disease?

What can we learn about depression symptoms in HD by studying mice - how do you know a mouse is even sad?

Dr Jeff CarrollJuly 17, 2013