Articles with the topic: animal-model

A recycled drug gives us new insight in to HD

A recycled drug gives us new insight in to HD

An existing drug could give a boost to HD brain cells – but it may need more testing before it’s back in the clinic

Dr Leora FoxDecember 15, 2015

Novel research technique suggests an antioxidant gene protects vulnerable neurons

Novel research technique suggests an antioxidant gene protects vulnerable neurons

Researchers use a new technique in an HD mouse to uncover a gene, Gpx6, that is protective to vulnerable neurons.

Dr Leora FoxApril 06, 2015

Building a Better Mouse(trap): A New Model of Huntington’s Disease

Building a Better Mouse(trap): A New Model of Huntington’s Disease

New mouse model gives insights into Huntington's disease

Melissa ChristiansonMarch 16, 2015

Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease

Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease

HD causes the normally helpful protein "ATM" to get a little overzealous. Now we can look for drugs to settle it down

Terry Jo BichellMarch 09, 2015

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

HD drug changes DNA folding across generations

Melissa ChristiansonFebruary 09, 2015

mTORC1 tips the scales in Huntington’s disease mice

mTORC1 tips the scales in Huntington’s disease mice

Weighing the scales on mTORC1: A possible new target for HD therapeutics?

Joseph OchabaJanuary 27, 2015

Should we worry about a huntingtin invasion?

Should we worry about a huntingtin invasion?

Cool lab experiments show the huntington's disease protein jumping between cells. Does this matter for HD patients?

Dr Jeff CarrollOctober 27, 2014

HD mice provide a useful failure

HD mice provide a useful failure

Can drug trials that fail be helpful? A HD mouse study provides solid evidence of an approach that doesn't help HD

Dr Jeff CarrollJuly 22, 2014

Illuminating the progression of Huntington’s disease

Illuminating the progression of Huntington’s disease

Researchers have used mice with glowing brain cells to decipher the first steps of neurodegeneration

Dr Tamara MaiuriJune 25, 2014

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