Articles with the topic: animal-model

HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease

HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease

Recent study in fruit flies identifies a new connection between synapses and HD

Dr Tamara MaiuriNovember 16, 2012

New experiments clarify the role of SIRT1 in HD - or do they?

New experiments clarify the role of SIRT1 in HD - or do they?

Work from multiple labs suggests activating a protein called SIRT1 might help HD, but the picture is still confusing

Dr Jeff CarrollJanuary 12, 2012

Bone marrow transplantation in Huntington's Disease

Bone marrow transplantation in Huntington's Disease

Bone marrow transplant protects HD mice from some symptoms, suggesting the immune system may be an important target

Dr Tony HannanJanuary 04, 2012

HDAC inhibitor drug protects memory in HD mice

HDAC inhibitor drug protects memory in HD mice

CBP, a gene-switching protein, protects memory in HD mice; 'histone deacetylase inhibitor' drug mimics its effects

Professor Ed WildDecember 13, 2011

Melatonin treatment success in HD mice

Melatonin treatment success in HD mice

Melatonin delays disease onset and extends survival in Huntington's disease mice – could it do the same for patients?

Professor Ed WildOctober 31, 2011

Protein-folding drug helps HD mice... for a while

Protein-folding drug helps HD mice... for a while

A drug that activates an ancient cellular defense mechanism slows down HD in mice – but why didn’t the benefit last?

Professor Ed WildAugust 23, 2011

Not all in your head: digestive problems in HD

Not all in your head: digestive problems in HD

Huntington's disease mice absorb less nutrition from food - which might help explain why human patients lose weight.

Dr Jeff CarrollJune 18, 2011

Chubby mice reveal the importance of the hypothalamus in Huntington's disease

Chubby mice reveal the importance of the hypothalamus in Huntington's disease

Huntington's disease mice are fat but HD patients lose weight – is a brain area called the hypothalamus to blame?

Professor Ed WildMay 02, 2011

What do sheep brains have to do with HD?

What do sheep brains have to do with HD?

How smart are sheep, and why do HD researchers care?

Dr Jeff CarrollMarch 09, 2011