Articles with the topic: animal-model

'Guard dog' proteins reveal surprising connections between Huntington's disease and other brain disorders

'Guard dog' proteins reveal surprising connections between Huntington's disease and other brain disorders

DNA/RNA-binding proteins may be involved in the damage caused by Huntington's disease and other major brain disorders

Melissa ChristiansonJanuary 10, 2013

Dyeing to prevent dying? Methylene blue beneficial in Huntington's disease mice

Dyeing to prevent dying? Methylene blue beneficial in Huntington's disease mice

A bolt from the blue - methylene blue may fight Huntington's disease by preventing protein clumps

Dr Tamara MaiuriJanuary 08, 2013

Targeting oxidative stress in Huntington's Disease

Targeting oxidative stress in Huntington's Disease

Damage to cells caused by oxidative stress is part of HD - could a new targeted drug help reduce this problem?

Dr Jeff CarrollDecember 03, 2012

Of mice and men: using animal models to study Huntington's disease

Of mice and men: using animal models to study Huntington's disease

Animal models of Huntington's disease: what they tell us about the disease and how can they help develop new therapie

Joseph OchabaNovember 29, 2012

HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease

HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease

Recent study in fruit flies identifies a new connection between synapses and HD

Dr Tamara MaiuriNovember 16, 2012

New experiments clarify the role of SIRT1 in HD - or do they?

New experiments clarify the role of SIRT1 in HD - or do they?

Work from multiple labs suggests activating a protein called SIRT1 might help HD, but the picture is still confusing

Dr Jeff CarrollJanuary 12, 2012

Bone marrow transplantation in Huntington's Disease

Bone marrow transplantation in Huntington's Disease

Bone marrow transplant protects HD mice from some symptoms, suggesting the immune system may be an important target

Dr Tony HannanJanuary 04, 2012

HDAC inhibitor drug protects memory in HD mice

HDAC inhibitor drug protects memory in HD mice

CBP, a gene-switching protein, protects memory in HD mice; 'histone deacetylase inhibitor' drug mimics its effects

Professor Ed WildDecember 13, 2011

Melatonin treatment success in HD mice

Melatonin treatment success in HD mice

Melatonin delays disease onset and extends survival in Huntington's disease mice – could it do the same for patients?

Professor Ed WildOctober 31, 2011

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