Articles with the topic: animal-model

Can sad mice help treat Huntington's disease?

Can sad mice help treat Huntington's disease?

What can we learn about depression symptoms in HD by studying mice - how do you know a mouse is even sad?

Dr Jeff CarrollJuly 17, 2013

A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene

A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene

DNA repair is a critical process to cells, but errors in this process might explain 'repeat instability' in HD

Carly DesmondJune 03, 2013

Prana Biotech publishes Huntington's disease animal model data for PBT2

Prana Biotech publishes Huntington's disease animal model data for PBT2

Prana Biotechnology has released data demonstrating their drug, PBT2, is effective in animal models of HD

Dr Jeff CarrollJanuary 14, 2013

'Guard dog' proteins reveal surprising connections between Huntington's disease and other brain disorders

'Guard dog' proteins reveal surprising connections between Huntington's disease and other brain disorders

DNA/RNA-binding proteins may be involved in the damage caused by Huntington's disease and other major brain disorders

Melissa ChristiansonJanuary 10, 2013

Dyeing to prevent dying? Methylene blue beneficial in Huntington's disease mice

Dyeing to prevent dying? Methylene blue beneficial in Huntington's disease mice

A bolt from the blue - methylene blue may fight Huntington's disease by preventing protein clumps

Dr Tamara MaiuriJanuary 08, 2013

Targeting oxidative stress in Huntington's Disease

Targeting oxidative stress in Huntington's Disease

Damage to cells caused by oxidative stress is part of HD - could a new targeted drug help reduce this problem?

Dr Jeff CarrollDecember 03, 2012

Of mice and men: using animal models to study Huntington's disease

Of mice and men: using animal models to study Huntington's disease

Animal models of Huntington's disease: what they tell us about the disease and how can they help develop new therapie

Joseph OchabaNovember 29, 2012

HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease

HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease

Recent study in fruit flies identifies a new connection between synapses and HD

Dr Tamara MaiuriNovember 16, 2012

New experiments clarify the role of SIRT1 in HD - or do they?

New experiments clarify the role of SIRT1 in HD - or do they?

Work from multiple labs suggests activating a protein called SIRT1 might help HD, but the picture is still confusing

Dr Jeff CarrollJanuary 12, 2012