Articles with the topic: animal-model

DNA shutdown proteins in Huntington's disease:  More than meets the eye

DNA shutdown proteins in Huntington's disease: More than meets the eye

Blocking HDAC4 improves Huntington's disease-related problems in cells and mice - but in a surprising way

Melissa ChristiansonDecember 16, 2013

What the 'big neurodegeneration breakthrough' means for Huntington's disease

What the 'big neurodegeneration breakthrough' means for Huntington's disease

Are recent findings in mice injected with 'prions' as important for Huntington's disease as widely reported?

Eric MinikelOctober 15, 2013

Could muscle problems help explain movements in Huntington’s Disease patients?

Could muscle problems help explain movements in Huntington’s Disease patients?

Proper contraction of muscles is crucial for coordination; errors in this process might help explain movements in HD

Dr Kurt JensenSeptember 06, 2013

Can sad mice help treat Huntington's disease?

Can sad mice help treat Huntington's disease?

What can we learn about depression symptoms in HD by studying mice - how do you know a mouse is even sad?

Dr Jeff CarrollJuly 17, 2013

A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene

A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene

DNA repair is a critical process to cells, but errors in this process might explain 'repeat instability' in HD

Carly DesmondJune 03, 2013

Prana Biotech publishes Huntington's disease animal model data for PBT2

Prana Biotech publishes Huntington's disease animal model data for PBT2

Prana Biotechnology has released data demonstrating their drug, PBT2, is effective in animal models of HD

Dr Jeff CarrollJanuary 14, 2013

'Guard dog' proteins reveal surprising connections between Huntington's disease and other brain disorders

'Guard dog' proteins reveal surprising connections between Huntington's disease and other brain disorders

DNA/RNA-binding proteins may be involved in the damage caused by Huntington's disease and other major brain disorders

Melissa ChristiansonJanuary 10, 2013

Dyeing to prevent dying? Methylene blue beneficial in Huntington's disease mice

Dyeing to prevent dying? Methylene blue beneficial in Huntington's disease mice

A bolt from the blue - methylene blue may fight Huntington's disease by preventing protein clumps

Dr Tamara MaiuriJanuary 08, 2013

Targeting oxidative stress in Huntington's Disease

Targeting oxidative stress in Huntington's Disease

Damage to cells caused by oxidative stress is part of HD - could a new targeted drug help reduce this problem?

Dr Jeff CarrollDecember 03, 2012