Articles with the topic: huntingtin-function

Enemy at the gates – huntingtin disrupts nuclear transport

Enemy at the gates – huntingtin disrupts nuclear transport

Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.

Tom PeskettApril 21, 2017

Huntingtin grabs a hammer: DNA repair in HD

Huntingtin grabs a hammer: DNA repair in HD

Huntingtin helps fix damaged DNA, a recent study suggests, under the direction of a gene repair protein called ATM.

Dr Leora FoxFebruary 22, 2017

The benefits of migration, highlighted in Huntington's disease

The benefits of migration, highlighted in Huntington's disease

Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again

Dr Michael FlowerFebruary 10, 2017

A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?

A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?

What if some problems in HD were due to something other than a harmful protein?

Dr Jeff CarrollDecember 30, 2016

Ultra-rare mutations highlight the importance of the HD gene in brain development

Ultra-rare mutations highlight the importance of the HD gene in brain development

New technology enables researchers to find ultra-rare mutations in the HD gene, distinct from the one causing HD

Megan KrenchAugust 29, 2016

Huntington's Disease Therapeutics Conference 2016 - day 1

Huntington's Disease Therapeutics Conference 2016 - day 1

Proteins and DNA - Jeff and Ed report from day 1 of the 2016 #huntingtonsdisease therapeutics conference

Dr Ed WildFebruary 25, 2016

Buzzilia Video: Day 1

Buzzilia Video: Day 1

Buzzilia video: Day 1. Highlights of the 2013 HD World Congress in Brazil: nightly news, interviews and features

Dr Jeff CarrollOctober 09, 2013

Video feature: Huntington's disease research... in space!

Video feature: Huntington's disease research... in space!

The sky's no longer the limit for HD research: HDBuzz interviews Gwen Owens, who's sending the HD protein into space!

Dr Ed WildSeptember 27, 2013

Does a 'rusty hinge' cause Huntington's disease?

Does a 'rusty hinge' cause Huntington's disease?

Canadian scientists have found that the mutant huntingtin protein is less flexible than normal.

Dr Ed WildAugust 27, 2013