Researchers show that highly expanded CAGs in the HD gene can cause early developmental changes using 3D brain models called organoids. What’d they find?
New insights into the huntingtin protein, and further progress in turning genetic quirks that modify the course of HD into treatments, on the final day of the therapeutics conference
Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein - and lowering it
A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?
Completely removing normal huntingtin in adults may disrupt healthy brain function, a recent study suggests.
HDBuzz summarises all the science from the 2017 Huntington's Disease Therapeutics Conference in Malta - day 1
Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.
Huntingtin helps fix damaged DNA, a recent study suggests, under the direction of a gene repair protein called ATM.
Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again