Articles with the topic: huntingtin-function

Huntington's disease therapeutics conference 2018 - day 3

Huntington's disease therapeutics conference 2018 - day 3

Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein - and lowering it

Dr Jeff CarrollMarch 02, 2018

An early role for the Huntington's disease gene – but don't believe all the headlines

An early role for the Huntington's disease gene – but don't believe all the headlines

A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?

Dr Jeff CarrollFebruary 27, 2018

New roles for huntingtin: removing a healthy protein to understand its function

New roles for huntingtin: removing a healthy protein to understand its function

Completely removing normal huntingtin in adults may disrupt healthy brain function, a recent study suggests.

Leora FoxSeptember 26, 2017

Huntington's Disease Therapeutics Conference 2017 - Day 1

Huntington's Disease Therapeutics Conference 2017 - Day 1

HDBuzz summarises all the science from the 2017 Huntington's Disease Therapeutics Conference in Malta - day 1

Dr Jeff CarrollApril 27, 2017

Enemy at the gates – huntingtin disrupts nuclear transport

Enemy at the gates – huntingtin disrupts nuclear transport

Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.

Tom PeskettApril 21, 2017

Huntingtin grabs a hammer: DNA repair in HD

Huntingtin grabs a hammer: DNA repair in HD

Huntingtin helps fix damaged DNA, a recent study suggests, under the direction of a gene repair protein called ATM.

Leora FoxFebruary 22, 2017

The benefits of migration, highlighted in Huntington's disease

The benefits of migration, highlighted in Huntington's disease

Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again

Dr Michael FlowerFebruary 10, 2017

A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?

A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?

What if some problems in HD were due to something other than a harmful protein?

Dr Jeff CarrollDecember 30, 2016

Ultra-rare mutations highlight the importance of the HD gene in brain development

Ultra-rare mutations highlight the importance of the HD gene in brain development

New technology enables researchers to find ultra-rare mutations in the HD gene, distinct from the one causing HD

Megan KrenchAugust 29, 2016