Exciting new Huntingtin Lowering work from @SangamoTx and @CHDIfoundation using "Zinc Fingers" to shut down expression of the mutant Huntingtin gene. More details on this exciting new technique here.
A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?
Media reports of a wonder drug for neurodegenerative diseases like Huntington's disease are overhyped
Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.
Huntingtin helps fix damaged DNA, a recent study suggests, under the direction of a gene repair protein called ATM.
Harmful misfolded huntingtin can travel between brain cells via messenger particles called exosomes
HD brain fluid makes brain cells grow clumps.
HD causes the normally helpful protein "ATM" to get a little overzealous. Now we can look for drugs to settle it down
Antibodies are known for their role in immunity, but researchers repurpose them in many ways. Can they be used in HD?