Articles with the topic: drug-development

Is a new Huntington’s Disease drug study on the right Trk?

Is a new Huntington’s Disease drug study on the right Trk?

A recent HD animal study reveals that a small molecule drug could be an effective “Trk” to target for HD therapeutics

Joseph OchabaJanuary 02, 2014

New study sheds light on regional degeneration in HD

New study sheds light on regional degeneration in HD

Why do certain brain cells die in HD? New research suggests is may be due to the efficiency of cellular recycling

Dr Kurt JensenNovember 12, 2013

What the 'big neurodegeneration breakthrough' means for Huntington's disease

What the 'big neurodegeneration breakthrough' means for Huntington's disease

Are recent findings in mice injected with 'prions' as important for Huntington's disease as widely reported?

Eric MinikelOctober 15, 2013

Targeting oxidative stress in Huntington's Disease

Targeting oxidative stress in Huntington's Disease

Damage to cells caused by oxidative stress is part of HD - could a new targeted drug help reduce this problem?

Dr Jeff CarrollDecember 03, 2012

Shooting the messenger with single-stranded RNA gene silencing

Shooting the messenger with single-stranded RNA gene silencing

New ‘single-stranded RNA’ gene silencing drugs could be safer & more effective to treat Huntington’s disease

Dr Nayana LahiriSeptember 24, 2012

Lithium with a twist gets second chance for HD

Lithium with a twist gets second chance for HD

Lithium gets a second chance in HD - with a new chemical delivery method, tested in Huntington’s disease mice

Carly DesmondSeptember 02, 2012

Phosphodiesterase inhibitors: new HD drugs entering trials soon

Phosphodiesterase inhibitors: new HD drugs entering trials soon

CHDI and Pfizer announce exciting animal work and plans for a human trial with a drug targeting 'phosphodiesterases'.

Carly DesmondJune 07, 2012

'Floating' gene-silencing drugs into the brain with exosomes

'Floating' gene-silencing drugs into the brain with exosomes

Exosomes – tiny bubbles made by cells – could be used to get gene silencing drugs from the bloodstream into the brain

Dr Ed WildMay 19, 2011

Focused drug screening leads to improved drugs to increase the rate of cellular recycling

Focused drug screening leads to improved drugs to increase the rate of cellular recycling

Advanced drug screening techniques help scientists to make drugs that increase cellular recycling in neurons.

Dr Jeff CarrollDecember 16, 2010