Articles with the topic: drug-development

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

HD drug changes DNA folding across generations

Melissa ChristiansonFebruary 09, 2015

mTORC1 tips the scales in Huntington’s disease mice

mTORC1 tips the scales in Huntington’s disease mice

Weighing the scales on mTORC1: A possible new target for HD therapeutics?

Joseph OchabaJanuary 27, 2015

Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

A clinical trial for an exciting therapy against HD is planned for 2015. The first step is to make sure it is safe.

Dr Leora FoxNovember 04, 2014

2CARE study of coenzyme Q for Huntington's disease ends in disappointment

2CARE study of coenzyme Q for Huntington's disease ends in disappointment

The largest ever HD drug trial, testing coenzyme Q10, is halted for 'futility'. What does that mean for HD research?

Dr Jeff CarrollAugust 13, 2014

Could HD be caused by amino acid deficiency?

Could HD be caused by amino acid deficiency?

Does a specific amino acid deficiency contribute to the development of HD?

Dr Jeff CarrollApril 21, 2014

Raptor announces results of cysteamine trial for Huntington's disease

Raptor announces results of cysteamine trial for Huntington's disease

Raptor Pharmaceuticals announces intermediate results from a long-term study of cysteamine in Huntington's disease

Dr Jeff CarrollApril 10, 2014

Huntington's Disease Therapeutics Conference 2014: day 1

Huntington's Disease Therapeutics Conference 2014: day 1

HDBuzz reports from the opening day of science sessions at the 2014 HD Therapeutics Conference in Palm Springs.

Professor Ed WildFebruary 26, 2014

Prana announces results of Reach2HD trial of PBT2 for Huntington's disease

Prana announces results of Reach2HD trial of PBT2 for Huntington's disease

Results are in for a clinical trial testing the drug PBT2 for HD. Are the claims in the announcement justified?

Dr Jeff CarrollFebruary 20, 2014

Does high-dose creatine "slow the onset" of Huntington's Disease?

Does high-dose creatine "slow the onset" of Huntington's Disease?

A new study claims that high-dose creatine "slows the onset of Huntington Disease". How much hope and how much hype?

Dr Jeff CarrollFebruary 11, 2014