Roche's 'brain shuttle' sneaks drugs past the blood-brain barrier. Could it work for HD gene silencing drugs?
A recent HD animal study reveals that a small molecule drug could be an effective “Trk” to target for HD therapeutics
Why do certain brain cells die in HD? New research suggests is may be due to the efficiency of cellular recycling
Are recent findings in mice injected with 'prions' as important for Huntington's disease as widely reported?
Damage to cells caused by oxidative stress is part of HD - could a new targeted drug help reduce this problem?
New ‘single-stranded RNA’ gene silencing drugs could be safer & more effective to treat Huntington’s disease
Lithium gets a second chance in HD - with a new chemical delivery method, tested in Huntington’s disease mice
CHDI and Pfizer announce exciting animal work and plans for a human trial with a drug targeting 'phosphodiesterases'.
Exosomes – tiny bubbles made by cells – could be used to get gene silencing drugs from the bloodstream into the brain