A collaborative team of scientists from Canada and Japan have identified a small molecule which can change the CAG-repeat length in different lab models of Huntington's disease. #HuntingtonsDisease #DrugDiscovery
Exciting new Huntingtin Lowering work from @SangamoTx and @CHDIfoundation using "Zinc Fingers" to shut down expression of the mutant Huntingtin gene. More details on this exciting new technique here.
Finally, a big study that shows what childhood HD looks like. This will help us work out if new drugs work in children too
A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?
What if some problems in HD were due to something other than a harmful protein?
New technology enables researchers to find ultra-rare mutations in the HD gene, distinct from the one causing HD
A new population study reveals that relatively mild forms of the HD mutation are much more common than we thought
Variety in the HD gene’s on switch affects when symptoms arise.