Search HDBuzz
Early exposure to the HD protein may cause life-long symptoms
A surprising new mouse study suggests the mutant HD gene may do some of its damage during embryonic development
June 28, 2016
Slightly long CAG repeats are more common than we thought
A new population study reveals that relatively mild forms of the HD mutation are much more common than we thought
July 05, 2016
Ultra-rare mutations highlight the importance of the HD gene in brain development
New technology enables researchers to find ultra-rare mutations in the HD gene, distinct from the one causing HD
August 29, 2016
A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?
What if some problems in HD were due to something other than a harmful protein?
December 30, 2016
A step forward for gene editing: CRISPR-Cas9 and HD
Evolving CRISPR-Cas9 techniques can now be used to edit the HD gene in a living mouse brain.
July 26, 2017
Success! ASO drug reduces levels of mutant protein in Huntington's disease patients
Amazing news from Ionis and Roche! HTTRx drug successfully lowers harmful huntingtin protein in spinal fluid
December 11, 2017
Huntington's disease therapeutics conference 2018 - day 3
Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein - and lowering it
March 02, 2018
Advances on many fronts in the battle against the protein that causes Huntington's disease
This fall sees exciting announcements from a number of companies focused on novel Huntingtin Lowering technologies, including Wave, PTC and Voyager
December 04, 2018
Huntington's disease therapeutics conference 2019 - Day 3
New insights into the huntingtin protein, and further progress in turning genetic quirks that modify the course of HD into treatments, on the final day of the therapeutics conference
March 05, 2019
When interrupting is good: genetic hiccups that protect against Huntington's disease
Multiple teams find small differences in the 'CAG repeat' bit of the Huntington's disease gene. They don't directly change the huntingtin protein, but do alter the age of symptom onset. What's behind this enigma and what does it mean for patients?
March 14, 2019
You can also read About HDBuzz for information on HDBuzz or try your search on a search engine.