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Update on the PTC Therapeutics PIVOT-HD Trial
Last week, PTC Therapeutics released a statement sharing that recruitment of participants into the US arm of the PIVOT-HD trial has been paused. In this article, we will lay out exactly what is known and what this announcement means.
November 03, 2022
Disappointing news from Novartis about branaplam and the VIBRANT-HD trial
Novartis have announced that they are ending development of the drug branaplam in Huntington’s disease. Here, we review this latest news and its impact on the HD community.
December 09, 2022
Hunting for balance: how the huntingtin protein compensates in HD
Researchers look at the cause and effect of various forms of the HTT protein. They find both expanded and unexpanded HTT contribute to brain cell communication and the brain has an amazing capacity to compensate for changes related to disease
April 05, 2023
Astrocytes: The new star in HD research?
A new article summarizes what the Huntington's disease field has found about a type of brain cell called an astrocyte. These star-shaped cells help keep brain cells healthy and could be leveraged for developing new HD therapeutics.
April 19, 2023
Huntington’s disease therapeutics conference 2023 - Day 1
Check out research updates from Day 1 of the 2022 HD Therapeutics Conference #HDTC2023
April 26, 2023
Huntington’s disease therapeutics conference 2023 - Day 2
Check out research updates from Day 2 of the 2022 HD Therapeutics Conference #HDTC2023
May 04, 2023
Huntington’s disease therapeutics conference 2023 - Day 3
Check out research updates from Day 3 of the 2022 HD Therapeutics Conference #HDTC2023
May 22, 2023
Updates from PTC Therapeutics and uniQure on their huntingtin-lowering trials
Both PTC Therapeutics and uniQure have shared updates from their respective clinical trials, testing different huntingtin-lowering approaches. We explore the data presented from both of these studies and what this means for HD family members.
June 21, 2023
Youthful competitors: young brain cells oust the old
Replacing cells with HD in the brain could be an effective treatment strategy. Recent work shows that glia injected into mouse brains take over and oust the older cells, but for a surprising reason - because of age, not HD!
August 08, 2023
Getting to the Root of Huntington's Disease: A Plant-Based Approach
Researchers used plants to study how to stop the Huntington’s disease protein from forming toxic clumps
October 15, 2023
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