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Picking MSH3’s Pocket: New Insights into CAG Repeat Expansion
8 min read
Latest News
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What Pigs Revealed that Mice Missed in Huntington’s Disease
9 min read
A change in one gene can disrupt thousands of others in HD. A study in pigs suggests an explanation: expanded huntingtin interferes with chemical marks on DNA. The same effect wasn’t seen in mice, showing that the animal model matters.
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Turning skin cells into brain cells: a Huntington's disease research breakthrough?
5 min read
Scientists can now change human skin cells into working neurons, like the ones that are most affected in HD.
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Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015
7 min read
A clinical trial for an exciting therapy against HD is planned for 2015. The first step is to make sure it is safe.
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Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis
4 min read
CREST-E, a trial of the supplement creatine, has been stopped after an early analysis found it couldn't show benefit
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Should we worry about a huntingtin invasion?
5 min read
Cool lab experiments show the huntington's disease protein jumping between cells. Does this matter for HD patients?
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EuroBuzz 2014 Video, day one
13 min read
Video of our first live session at the European Huntington's Disease Network Meeting.
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EuroBuzz 2014 Video, day two
21 min read
Video of our second live session at the European Huntington's Disease Network Meeting.
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Melatonin alterations in Huntington's disease help explain trouble with sleep
7 min read
Study shows HD patients have decreased levels of melatonin, which may explain why so many suffer from sleep problems
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EuroBuzz 2014: day three
4 min read
Our third and final report on the 2014 European Huntington's Disease Network meeting in Barcelona
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EuroBuzz 2014: day two
7 min read
HDBuzz reports on the second day of science at the European HD Network meeting in Barcelona
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EuroBuzz 2014: day one
11 min read
Highlights from the opening day of the 2014 European Huntington's Disease network in Barcelona, Spain
HDBuzz Trial Tracker
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Updates from the ongoing Phase 3 INVEST-HD trial of votoplam
Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01
Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515
