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Picking MSH3’s Pocket: New Insights into CAG Repeat Expansion
8 min read
Latest News
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What Pigs Revealed that Mice Missed in Huntington’s Disease
9 min read
A change in one gene can disrupt thousands of others in HD. A study in pigs suggests an explanation: expanded huntingtin interferes with chemical marks on DNA. The same effect wasn’t seen in mice, showing that the animal model matters.
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Raptor announces results of cysteamine trial for Huntington's disease
10 min read
Raptor Pharmaceuticals announces intermediate results from a long-term study of cysteamine in Huntington's disease
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Sleep, cilia and HD
9 min read
New studies shed some light on the function of sleep in animals, with interesting implications for HD research
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Huntington's Disease Therapeutics Conference 2014: day 3
8 min read
Biomarkers and preparing for trials: the third & final day of the 2014 Huntington's Disease Therapeutics Conference
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Huntington's Disease Therapeutics Conference 2014: day 2
5 min read
Cells, circuits and systems: day 2 of the 2014 HD Therapeutics conference
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Huntington's Disease Therapeutics Conference 2014: day 1
10 min read
HDBuzz reports from the opening day of science sessions at the 2014 HD Therapeutics Conference in Palm Springs.
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Prana announces results of Reach2HD trial of PBT2 for Huntington's disease
12 min read
Results are in for a clinical trial testing the drug PBT2 for HD. Are the claims in the announcement justified?
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Does high-dose creatine "slow the onset" of Huntington's Disease?
7 min read
A new study claims that high-dose creatine "slows the onset of Huntington Disease". How much hope and how much hype?
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Joint HDBuzz Prizewinner: Yeast studies suggest a new way to protect cells from 'oxidative damage'
7 min read
Researchers identify Gpx1, a protein that may be protective in HD. An existing drug can mimic its antioxidant effect.
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Joint HDBuzz Prizewinner: Pennies for your neurons — copper’s bad influence on Huntington’s disease
7 min read
There is copper in your brain! Check out how copper and the Huntington’s disease protein are partners in crime.
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Could a 'brain shuttle' get Huntington's disease drugs to where they're needed?
5 min read
Roche's 'brain shuttle' sneaks drugs past the blood-brain barrier. Could it work for HD gene silencing drugs?
HDBuzz Trial Tracker
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Updates from the ongoing Phase 3 INVEST-HD trial of votoplam
Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01
Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515
