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Picking MSH3’s Pocket: New Insights into CAG Repeat Expansion
8 min read
Latest News
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What Pigs Revealed that Mice Missed in Huntington’s Disease
9 min read
A change in one gene can disrupt thousands of others in HD. A study in pigs suggests an explanation: expanded huntingtin interferes with chemical marks on DNA. The same effect wasn’t seen in mice, showing that the animal model matters.
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TRACK-HD reveals significant changes in pre-symptomatic HD mutation carriers and patients
7 min read
The one-year report from the TRACK-HD study demonstrates a number of changes in pre-symptomatic HD-mutation carriers
HDBuzz Trial Tracker
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Updates from the ongoing Phase 3 INVEST-HD trial of votoplam
Novartis/PTC Therapeutics
Expected:
Not disclosed
Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01
University of California, Irvine
Expected:
Not disclosed
Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515
Skyhawk Therapeutics
Expected:
Not disclosed
