A multiple sclerosis drug that works for Huntington's disease: the real deal or too good to be true?

A multiple sclerosis drug that works for Huntington's disease: the real deal or too good to be true?

Fingolimod, a drug used in multiple sclerosis, prevents memory problems in HD mice. Would it work in patients?

Melissa ChristiansonNovember 24, 2015

Mapping the anatomy of HD: a whole-brain history

Mapping the anatomy of HD: a whole-brain history

A new book for researchers describes a century of HD anatomy and presents evidence that HD affects the whole brain.

Leora FoxNovember 04, 2015

Liftoff: First humans treated with gene silencing drugs for HD!

Liftoff: First humans treated with gene silencing drugs for HD!

Major Announcement: First HD patients treated with gene silencing drugs

Dr Jeff CarrollOctober 22, 2015

HDBuzz primer: Clinical trial designs and phases

HDBuzz primer: Clinical trial designs and phases

HDBuzz untangles hope from hype in clinical trial announcements

Dr Jeff Carroll and Melissa ChristiansonOctober 09, 2015

A Few Bad Seeds: Using Brain Fluid to Grow Clumps in Brain Cells

A Few Bad Seeds: Using Brain Fluid to Grow Clumps in Brain Cells

HD brain fluid makes brain cells grow clumps.

Melissa ChristiansonSeptember 15, 2015

New tool to measure outcomes in Huntington’s Disease clinical trials

New tool to measure outcomes in Huntington’s Disease clinical trials

A better tool for HD trials! New research shows innovative way to measure mutant Huntingtin outside the brain

Megan KrenchSeptember 03, 2015

Huge study reveals new 'genetic modifiers' of Huntington's disease

Huge study reveals new 'genetic modifiers' of Huntington's disease

GeM-HD identifies the first solid leads in the hunt for genetic variations that affect Huntington's disease onset

Dr Jeff CarrollJuly 31, 2015

Would ewe believe it? GM1, sheep and Huntington's disease

Would ewe believe it? GM1, sheep and Huntington's disease

HD researchers and sheep farmers are collaborating on a brain fat called GM1, but a clinical trial is a long way off

Leora FoxJuly 28, 2015

Switching it up: variety in the HD gene affects symptom onset

Switching it up: variety in the HD gene affects symptom onset

Variety in the HD gene’s on switch affects when symptoms arise.

Melissa ChristiansonMay 29, 2015

Measuring harmful huntingtin protein in the brain’s bath water

Measuring harmful huntingtin protein in the brain’s bath water

How will we know whether HD-lowering treatments are working? New advancements in the detection of mutant huntingtin.

Dr Michael OrthMay 18, 2015

A faulty filter? Blood vessel changes in Huntington's disease

A faulty filter? Blood vessel changes in Huntington's disease

New research reveals blood vessel changes that could contribute to problem in HD

Melissa ChristiansonMay 13, 2015