animal-model
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DNA shutdown proteins in Huntington's disease: More than meets the eye
Blocking HDAC4 improves Huntington's disease-related problems in cells and mice – but in a surprising way
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What the 'big neurodegeneration breakthrough' means for Huntington's disease
Are recent findings in mice injected with 'prions' as important for Huntington's disease as widely reported?
By Eric Minikel -
Could muscle problems help explain movements in Huntington’s Disease patients?
Proper contraction of muscles is crucial for coordination; errors in this process might help explain movements in HD
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Can sad mice help treat Huntington's disease?
What can we learn about depression symptoms in HD by studying mice – how do you know a mouse is even sad?
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A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene
DNA repair is a critical process to cells, but errors in this process might explain 'repeat instability' in HD
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Prana Biotech publishes Huntington's disease animal model data for PBT2
Prana Biotechnology has released data demonstrating their drug, PBT2, is effective in animal models of HD
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'Guard dog' proteins reveal surprising connections between Huntington's disease and other brain disorders
DNA/RNA-binding proteins may be involved in the damage caused by Huntington's disease and other major brain disorders
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Dyeing to prevent dying? Methylene blue beneficial in Huntington's disease mice
A bolt from the blue – methylene blue may fight Huntington's disease by preventing protein clumps
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Targeting oxidative stress in Huntington's Disease
Damage to cells caused by oxidative stress is part of HD – could a new targeted drug help reduce this problem?
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Of mice and men: using animal models to study Huntington's disease
Animal models of Huntington's disease: what they tell us about the disease and how can they help develop new therapie