animal-model
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'Guard dog' proteins reveal surprising connections between Huntington's disease and other brain disorders
7 min read
DNA/RNA-binding proteins may be involved in the damage caused by Huntington's disease and other major brain disorders
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Dyeing to prevent dying? Methylene blue beneficial in Huntington's disease mice
7 min read
A bolt from the blue – methylene blue may fight Huntington's disease by preventing protein clumps
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Targeting oxidative stress in Huntington's Disease
5 min read
Damage to cells caused by oxidative stress is part of HD – could a new targeted drug help reduce this problem?
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Of mice and men: using animal models to study Huntington's disease
8 min read
Animal models of Huntington's disease: what they tell us about the disease and how can they help develop new therapie
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HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease
5 min read
Recent study in fruit flies identifies a new connection between synapses and HD
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New experiments clarify the role of SIRT1 in HD – or do they?
7 min read
Work from multiple labs suggests activating a protein called SIRT1 might help HD, but the picture is still confusing
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Bone marrow transplantation in Huntington's Disease
5 min read
Bone marrow transplant protects HD mice from some symptoms, suggesting the immune system may be an important target
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HDAC inhibitor drug protects memory in HD mice
8 min read
CBP, a gene-switching protein, protects memory in HD mice; 'histone deacetylase inhibitor' drug mimics its effects
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Melatonin treatment success in HD mice
9 min read
Melatonin delays disease onset and extends survival in Huntington's disease mice – could it do the same for patients?
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Protein-folding drug helps HD mice… for a while
6 min read
A drug that activates an ancient cellular defense mechanism slows down HD in mice – but why didn’t the benefit last?