animal-model
-
Early exposure to the HD protein may cause life-long symptoms
8 min read
A surprising new mouse study suggests the mutant HD gene may do some of its damage during embryonic development
-
Harnessing the power of viruses to treat Huntington's disease
7 min read
Researchers design a virus to more effectively deliver gene-silencing drugs throughout the brain.
By Dr Leora Fox -
A recycled drug gives us new insight in to HD
7 min read
An existing drug could give a boost to HD brain cells – but it may need more testing before it’s back in the clinic
By Dr Leora Fox -
Novel research technique suggests an antioxidant gene protects vulnerable neurons
8 min read
Researchers use a new technique in an HD mouse to uncover a gene, Gpx6, that is protective to vulnerable neurons.
By Dr Leora Fox -
Building a Better Mouse(trap): A New Model of Huntington’s Disease
7 min read
New mouse model gives insights into Huntington's disease
-
Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease
6 min read
HD causes the normally helpful protein "ATM" to get a little overzealous. Now we can look for drugs to settle it down
-
Drug Improves Huntington’s Symptoms in Mice – and Their Offspring
7 min read
HD drug changes DNA folding across generations
-
mTORC1 tips the scales in Huntington’s disease mice
6 min read
Weighing the scales on mTORC1: A possible new target for HD therapeutics?
-
Should we worry about a huntingtin invasion?
5 min read
Cool lab experiments show the huntington's disease protein jumping between cells. Does this matter for HD patients?
-
HD mice provide a useful failure
5 min read
Can drug trials that fail be helpful? A HD mouse study provides solid evidence of an approach that doesn't help HD