A new imaging tool means that scientists can now directly measure the levels of the toxic huntingtin protein in animal models of Huntington’s disease, letting us see how well huntingtin lowering therapies are working in their brains
Exciting new Huntingtin Lowering work from @SangamoTx and @CHDIfoundation using "Zinc Fingers" to shut down expression of the mutant Huntingtin gene. More details on this exciting new technique here.
HDBuzz reports from the annual Huntington’s disease therapeutics conference in Palm Springs
A new book for researchers describes a century of HD anatomy and presents evidence that HD affects the whole brain.
New research reveals blood vessel changes that could contribute to problem in HD
New observations suggest that the brains of HD mutation carriers consume energy differently. Do we care? (Yes!)
A new brain scanning technique reveals high sodium levels in HD brains. How might this help clinical trials?
Smaller total brain volumes in male HD mutation carriers suggests brain development may be different in HD.