Articles with the topic: mouse-model

Sleep, cilia and HD

Sleep, cilia and HD

New studies shed some light on the function of sleep in animals, with interesting implications for HD research

Graham EastonMarch 06, 2014

Calming down the immune system helps Huntington's disease mice

Calming down the immune system helps Huntington's disease mice

CB2-activating drug improves survival and symptoms in Huntington's disease mice through calming down the immune syste

Professor Ed WildDecember 22, 2012

Of mice and men: using animal models to study Huntington's disease

Of mice and men: using animal models to study Huntington's disease

Animal models of Huntington's disease: what they tell us about the disease and how can they help develop new therapie

Joseph OchabaNovember 29, 2012

Shooting the messenger with single-stranded RNA gene silencing

Shooting the messenger with single-stranded RNA gene silencing

New ‘single-stranded RNA’ gene silencing drugs could be safer & more effective to treat Huntington’s disease

Dr Nayana LahiriSeptember 24, 2012

Lithium with a twist gets second chance for HD

Lithium with a twist gets second chance for HD

Lithium gets a second chance in HD - with a new chemical delivery method, tested in Huntington’s disease mice

Carly DesmondSeptember 02, 2012

Mapping the neighborhood: huntingtin's new protein partners

Mapping the neighborhood: huntingtin's new protein partners

Study of huntingtin protein's 'neighbors' reveals dozens of new drug development targets

Dr Jeff CarrollAugust 13, 2012

Special 'brain fat' injection helps HD mice

Special 'brain fat' injection helps HD mice

Directly injecting the brains of HD mice with a good type of fat called ganglioside GM1 provides dramatic benefit

Dr Jeff CarrollFebruary 14, 2012

Turning down the volume with dantrolene helps HD mice

Turning down the volume with dantrolene helps HD mice

Dantrolene, an muscle-relaxer drug already on the market, helps HD mice by reducing cellular calcium levels

Dr Jeff CarrollDecember 08, 2011

Gene silencing takes a targeted step forward

Gene silencing takes a targeted step forward

Targeting the mutant Huntington's disease gene for silencing, while leaving the healthy gene untouched

Dr Michael OrthOctober 07, 2011

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