Articles with the topic: mouse-model

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

HD drug changes DNA folding across generations

Melissa ChristiansonFebruary 09, 2015

mTORC1 tips the scales in Huntington’s disease mice

mTORC1 tips the scales in Huntington’s disease mice

Weighing the scales on mTORC1: A possible new target for HD therapeutics?

Joseph OchabaJanuary 27, 2015

New results bring BDNF therapies into focus

New results bring BDNF therapies into focus

Some unexpected findings suggest new ways to aim at an old target in HD

Dr Jeff CarrollAugust 18, 2014

HD mice provide a useful failure

HD mice provide a useful failure

Can drug trials that fail be helpful? A HD mouse study provides solid evidence of an approach that doesn't help HD

Dr Jeff CarrollJuly 22, 2014

Illuminating the progression of Huntington’s disease

Illuminating the progression of Huntington’s disease

Researchers have used mice with glowing brain cells to decipher the first steps of neurodegeneration

Dr Tamara MaiuriJune 25, 2014

Could HD be caused by amino acid deficiency?

Could HD be caused by amino acid deficiency?

Does a specific amino acid deficiency contribute to the development of HD?

Dr Jeff CarrollApril 21, 2014

Sleep, cilia and HD

Sleep, cilia and HD

New studies shed some light on the function of sleep in animals, with interesting implications for HD research

Graham EastonMarch 06, 2014

Calming down the immune system helps Huntington's disease mice

Calming down the immune system helps Huntington's disease mice

CB2-activating drug improves survival and symptoms in Huntington's disease mice through calming down the immune syste

Professor Ed WildDecember 22, 2012

Of mice and men: using animal models to study Huntington's disease

Of mice and men: using animal models to study Huntington's disease

Animal models of Huntington's disease: what they tell us about the disease and how can they help develop new therapie

Joseph OchabaNovember 29, 2012