Articles with the topic: mouse-model

Novel research technique suggests an antioxidant gene protects vulnerable neurons

Novel research technique suggests an antioxidant gene protects vulnerable neurons

Researchers use a new technique in an HD mouse to uncover a gene, Gpx6, that is protective to vulnerable neurons.

Dr Leora FoxApril 06, 2015

Building a Better Mouse(trap): A New Model of Huntington’s Disease

Building a Better Mouse(trap): A New Model of Huntington’s Disease

New mouse model gives insights into Huntington's disease

Melissa ChristiansonMarch 16, 2015

Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease

Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease

HD causes the normally helpful protein "ATM" to get a little overzealous. Now we can look for drugs to settle it down

Terry Jo BichellMarch 09, 2015

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

HD drug changes DNA folding across generations

Melissa ChristiansonFebruary 09, 2015

mTORC1 tips the scales in Huntington’s disease mice

mTORC1 tips the scales in Huntington’s disease mice

Weighing the scales on mTORC1: A possible new target for HD therapeutics?

Joseph OchabaJanuary 27, 2015

New results bring BDNF therapies into focus

New results bring BDNF therapies into focus

Some unexpected findings suggest new ways to aim at an old target in HD

Dr Jeff CarrollAugust 18, 2014

HD mice provide a useful failure

HD mice provide a useful failure

Can drug trials that fail be helpful? A HD mouse study provides solid evidence of an approach that doesn't help HD

Dr Jeff CarrollJuly 22, 2014

Illuminating the progression of Huntington’s disease

Illuminating the progression of Huntington’s disease

Researchers have used mice with glowing brain cells to decipher the first steps of neurodegeneration

Dr Tamara MaiuriJune 25, 2014

Could HD be caused by amino acid deficiency?

Could HD be caused by amino acid deficiency?

Does a specific amino acid deficiency contribute to the development of HD?

Dr Jeff CarrollApril 21, 2014

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