Articles with the topic: post-translational-modification

Does a 'rusty hinge' cause Huntington's disease?

Does a 'rusty hinge' cause Huntington's disease?

Canadian scientists have found that the mutant huntingtin protein is less flexible than normal.

Professor Ed WildAugust 27, 2013

The 'N17' region of huntingtin protein: an address label in Huntington's disease?

The 'N17' region of huntingtin protein: an address label in Huntington's disease?

New research sheds light on where the huntingtin protein ends up inside our cells, and why

Joseph OchabaFebruary 26, 2013

Special 'brain fat' injection helps HD mice

Special 'brain fat' injection helps HD mice

Directly injecting the brains of HD mice with a good type of fat called ganglioside GM1 provides dramatic benefit

Dr Jeff CarrollFebruary 14, 2012

Re-routing the huntingtin protein inside cells

Re-routing the huntingtin protein inside cells

Canadian team decodes the tags that re-route the huntingtin protein within cells, helping explain how it becomes toxi

Dr Jeff CarrollJune 26, 2011