Articles with the topic: aggregates

A first for CRISPR gene editing could have wider applications for human disease

A first for CRISPR gene editing could have wider applications for human disease

A successful early trial of a drug for Familial Transthyretic Amyloidosis showed that CRISPR gene editing could be safely used in the human body. What does this mean for gene editing in HD?

Daniel O’ReillyJuly 21, 2021

Has a "wonder drug" for dementia been discovered? (Spoiler alert: no.)

Has a "wonder drug" for dementia been discovered? (Spoiler alert: no.)

Media reports of a wonder drug for neurodegenerative diseases like Huntington's disease are overhyped

Dr Michael FlowerMay 07, 2017

Enemy at the gates – huntingtin disrupts nuclear transport

Enemy at the gates – huntingtin disrupts nuclear transport

Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.

Tom PeskettApril 21, 2017

Huntingtin takes a trip: harmful proteins pass between brain cells

Huntingtin takes a trip: harmful proteins pass between brain cells

Harmful misfolded huntingtin can travel between brain cells via messenger particles called exosomes

Dr Leora FoxJune 06, 2016

A Few Bad Seeds: Using Brain Fluid to Grow Clumps in Brain Cells

A Few Bad Seeds: Using Brain Fluid to Grow Clumps in Brain Cells

HD brain fluid makes brain cells grow clumps.

Melissa ChristiansonSeptember 15, 2015

Should we worry about a huntingtin invasion?

Should we worry about a huntingtin invasion?

Cool lab experiments show the huntington's disease protein jumping between cells. Does this matter for HD patients?

Dr Jeff CarrollOctober 27, 2014

Going toe-to-toe with tau: new insights into the chemical basis of Huntington’s disease

Going toe-to-toe with tau: new insights into the chemical basis of Huntington’s disease

Does tau protein – which causes problems in other neurodegenerative diseases – contribute to Huntington's disease?

Siddharth NathSeptember 13, 2014

Jumping genes: Huntington's disease protein invades brain transplants

Jumping genes: Huntington's disease protein invades brain transplants

A long-term study of the brains of HD patients who received grafts of fetal tissue reveals a surprising result

Dr Jeff CarrollMay 26, 2014

Raptor announces results of cysteamine trial for Huntington's disease

Raptor announces results of cysteamine trial for Huntington's disease

Raptor Pharmaceuticals announces intermediate results from a long-term study of cysteamine in Huntington's disease

Dr Jeff CarrollApril 10, 2014