Articles with the topic: biomarkers

Listening for Whispers: How a Tiny Protein Could Transform HD Research

Listening for Whispers: How a Tiny Protein Could Transform HD Research

A 14-year study tracking NfL levels in people with the HD gene shows this tiny protein can signal disease progression many years before symptoms start. The longest follow-up study yet adds weight to NfL as a powerful tool for HD research.

Dr Tamara MaiuriMarch 13, 2025

Huntington’s Disease Clinical Expert Prof. Ed Wild Shares Hopeful View For 2025

Huntington’s Disease Clinical Expert Prof. Ed Wild Shares Hopeful View For 2025

The HDBuzz team caught up with editor emeritus and Huntington's disease specialist, Prof Ed Wild to hear his thoughts on what 2025 has in store for the Huntington's disease community

Dr Rachel HardingJanuary 27, 2025

Spotting HD Early: The Clues Hidden in Young Brains

Spotting HD Early: The Clues Hidden in Young Brains

Researchers have detected early changes in brain scans and biomarkers in young people with the Huntington’s disease gene, 20 years before symptoms are predicted to appear. These findings could help develop medicines to treat HD earlier in life.

Dr Rachel HardingJanuary 17, 2025

2024: Year in Review

2024: Year in Review

As we begin 2025, we look back on all of the Huntington’s disease research news and progress the field has made in the last 12 months.

Dr Rachel HardingJanuary 02, 2025

Cry your eyes out: detecting huntingtin in tears

Cry your eyes out: detecting huntingtin in tears

Is someone cutting onions? Expanded huntingtin can now be detected in tears to help scientists track disease progression.

Dr Sarah HernandezApril 10, 2024

Huntington’s disease therapeutics conference 2023 - Day 3

Huntington’s disease therapeutics conference 2023 - Day 3

Check out research updates from Day 3 of the 2022 HD Therapeutics Conference #HDTC2023

Joel Stanton, Dr Rachel Harding, Dr Leora Fox, and Dr Tamara MaiuriMay 22, 2023

Hereditary Disease Foundation (HDF) conference 2022 – Day 1

Hereditary Disease Foundation (HDF) conference 2022 – Day 1

Read updates from clinical trials and scientific research on Huntington’s disease from Day 1 of the 2022 HDF Milton Wexler Biennial Symposium #HDF2022

Dr Rachel Harding and Dr Sarah HernandezAugust 31, 2022

Updates from uniQure about their gene therapy for Huntington's disease

Updates from uniQure about their gene therapy for Huntington's disease

uniQure is conducting safety trials of the first gene therapy for HD. A recent press release provided a 1 year update on the first group of 10 people who underwent surgery to receive this experimental drug. Let’s talk more about what it means.

Dr Leora Fox and Dr Rachel HardingJuly 11, 2022

Does blood hold the key to testing treatments earlier in HD patients?

Does blood hold the key to testing treatments earlier in HD patients?

A new study by researchers at Johns Hopkins describes a non-invasive way to track progression of Huntington’s disease. This could be used before patients even start showing symptoms to help test treatments in early stages of disease.

Dr Rachel HardingAugust 04, 2021

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