Articles with the topic: clinical-trial

Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis

Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis

CREST-E, a trial of the supplement creatine, has been stopped after an early analysis found it couldn't show benefit

Dr Ed WildOctober 29, 2014

2CARE study of coenzyme Q for Huntington's disease ends in disappointment

2CARE study of coenzyme Q for Huntington's disease ends in disappointment

The largest ever HD drug trial, testing coenzyme Q10, is halted for 'futility'. What does that mean for HD research?

Dr Jeff CarrollAugust 13, 2014

HD mice provide a useful failure

HD mice provide a useful failure

Can drug trials that fail be helpful? A HD mouse study provides solid evidence of an approach that doesn't help HD

Dr Jeff CarrollJuly 22, 2014

Raptor announces results of cysteamine trial for Huntington's disease

Raptor announces results of cysteamine trial for Huntington's disease

Raptor Pharmaceuticals announces intermediate results from a long-term study of cysteamine in Huntington's disease

Dr Jeff CarrollApril 10, 2014

Prana announces results of Reach2HD trial of PBT2 for Huntington's disease

Prana announces results of Reach2HD trial of PBT2 for Huntington's disease

Results are in for a clinical trial testing the drug PBT2 for HD. Are the claims in the announcement justified?

Dr Jeff CarrollFebruary 20, 2014

Does high-dose creatine "slow the onset" of Huntington's Disease?

Does high-dose creatine "slow the onset" of Huntington's Disease?

A new study claims that high-dose creatine "slows the onset of Huntington Disease". How much hope and how much hype?

Dr Jeff CarrollFebruary 11, 2014

More evidence points to Huntington's disease exercise benefit

More evidence points to Huntington's disease exercise benefit

Two studies show exercise benefits for some symptoms of Huntington's disease. Just don't believe everything you read.

Dr Tamara MaiuriDecember 09, 2013

HDBuzz Prize winner 2012: Deep brain stimulation for HD

HDBuzz Prize winner 2012: Deep brain stimulation for HD

HDBuzz Prizewinner 2012: Deep brain stimulation to treat uncontrollable movements called chorea in Huntington's disea

Melissa ChristiansonOctober 29, 2012

Prana Biotech's new trial of PBT2 in Huntington's disease: the lowdown

Prana Biotech's new trial of PBT2 in Huntington's disease: the lowdown

Prana Biotech's PBT2 trial in Huntington's disease: what we know so far & what copper has to do with the mutant prote

Dr Ed WildOctober 03, 2011