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'Guard dog' proteins reveal surprising connections between Huntington's disease and other brain disorders

'Guard dog' proteins reveal surprising connections between Huntington's disease and other brain disorders

DNA/RNA-binding proteins may be involved in the damage caused by Huntington's disease and other major brain disorders

Melissa ChristiansonJanuary 10, 2013

HDBuzz Special Feature: Huntington's disease and sleep

HDBuzz Special Feature: Huntington's disease and sleep

Why do many Huntington's disease patients have trouble sleeping, and what can be done about it?

Prof Jenny MortonFebruary 06, 2013

The 'N17' region of huntingtin protein: an address label in Huntington's disease?

The 'N17' region of huntingtin protein: an address label in Huntington's disease?

New research sheds light on where the huntingtin protein ends up inside our cells, and why

Joseph OchabaFebruary 26, 2013

Liver changes in Huntington's disease patients suggest more 'whole body' research needed

Liver changes in Huntington's disease patients suggest more 'whole body' research needed

A new study suggests that liver changes may occur in HD patients, opening up new avenues of research

Dr Jeff CarrollMarch 06, 2013

Major Roche-Isis deal boosts Huntington's disease gene silencing

Major Roche-Isis deal boosts Huntington's disease gene silencing

'ASO' gene silencing drugs for HD boosted by major deal between Isis Pharmaceuticals and Roche

Professor Ed WildApril 09, 2013

HD Therapeutics Conference 2013 Updates: Day 1

HD Therapeutics Conference 2013 Updates: Day 1

Day 1 of our coverage of the Huntington's Disease Therapeutics Conference

Dr Jeff CarrollApril 09, 2013

A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene

A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene

DNA repair is a critical process to cells, but errors in this process might explain 'repeat instability' in HD

Carly DesmondJune 03, 2013

Gene silencing drug safe in ALS patients... bring on Huntington's disease trials

Gene silencing drug safe in ALS patients... bring on Huntington's disease trials

Gene silencing drug injected into spinal fluid in ALS patients proves safe. Good news for similar planned HD trials.

Joseph OchabaJune 29, 2013

How long is too long? Rethinking the Huntington’s disease ‘gray area’

How long is too long? Rethinking the Huntington’s disease ‘gray area’

Does an ‘intermediate’ CAG repeat count in the Huntington’s disease gene cause brain changes?

Dr Peter McColganAugust 19, 2013

Does a 'rusty hinge' cause Huntington's disease?

Does a 'rusty hinge' cause Huntington's disease?

Canadian scientists have found that the mutant huntingtin protein is less flexible than normal.

Professor Ed WildAugust 27, 2013

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