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Novel research technique suggests an antioxidant gene protects vulnerable neurons

Novel research technique suggests an antioxidant gene protects vulnerable neurons

Researchers use a new technique in an HD mouse to uncover a gene, Gpx6, that is protective to vulnerable neurons.

Dr Leora FoxApril 06, 2015

A recycled drug gives us new insight in to HD

A recycled drug gives us new insight in to HD

An existing drug could give a boost to HD brain cells – but it may need more testing before it’s back in the clinic

Dr Leora FoxDecember 15, 2015

The benefits of migration, highlighted in Huntington's disease

The benefits of migration, highlighted in Huntington's disease

Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again

Dr Michael FlowerFebruary 10, 2017

Enemy at the gates – huntingtin disrupts nuclear transport

Enemy at the gates – huntingtin disrupts nuclear transport

Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.

Tom PeskettApril 21, 2017

Huntington's Disease Therapeutics Conference 2017 - Day 1

Huntington's Disease Therapeutics Conference 2017 - Day 1

HDBuzz summarises all the science from the 2017 Huntington's Disease Therapeutics Conference in Malta - day 1

Dr Jeff CarrollApril 27, 2017

Huntington's Disease Therapeutics Conference 2017 - Day 3

Huntington's Disease Therapeutics Conference 2017 - Day 3

HDBuzz summarises final day of the 2017 Huntington's Disease Therapeutics Conference in Malta

Professor Ed WildApril 30, 2017

An early role for the Huntington's disease gene – but don't believe all the headlines

An early role for the Huntington's disease gene – but don't believe all the headlines

A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?

Dr Jeff CarrollFebruary 27, 2018

Kids sometimes get Huntington’s disease too

Kids sometimes get Huntington’s disease too

Finally, a big study that shows what childhood HD looks like. This will help us work out if new drugs work in children too

Dr Michael FlowerOctober 10, 2018

Huntington's disease therapeutics conference 2019 - Day 3

Huntington's disease therapeutics conference 2019 - Day 3

New insights into the huntingtin protein, and further progress in turning genetic quirks that modify the course of HD into treatments, on the final day of the therapeutics conference

Joel Stanton and Dr Jeff CarrollMarch 05, 2019

When interrupting is good: genetic hiccups that protect against Huntington's disease

When interrupting is good: genetic hiccups that protect against Huntington's disease

Multiple teams find small differences in the 'CAG repeat' bit of the Huntington's disease gene. They don't directly change the huntingtin protein, but do alter the age of symptom onset. What's behind this enigma and what does it mean for patients?

Dr Jeff CarrollMarch 14, 2019

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