Search HDBuzz
'Floating' gene-silencing drugs into the brain with exosomes
Exosomes – tiny bubbles made by cells – could be used to get gene silencing drugs from the bloodstream into the brain
May 19, 2011
Gene silencing takes a targeted step forward
Targeting the mutant Huntington's disease gene for silencing, while leaving the healthy gene untouched
October 07, 2011
Safety trials add crucial piece to gene silencing jigsaw
Three trials of drugs to 'silence' the HD gene in monkeys show they hit the target safely. Human trials coming soon.
November 14, 2011
Double success for huntingtin RNAi gene silencing
2 bits of good news for RNAi gene silencing in HD: it's safe over six months, and a way to treat bigger brain areas
January 24, 2012
Could mesenchymal stem cells deliver gene silencing drugs?
Stem cells can deliver HD gene silencing drugs into cells in a dish. Do we need another delivery technology?
January 31, 2012
ASO gene silencing reaches further, lasts longer
Silencing the Huntingtin gene using ASO drugs reaches further, lasts longer and is safe. Human trial soon?
June 21, 2012
Shooting the messenger with single-stranded RNA gene silencing
New ‘single-stranded RNA’ gene silencing drugs could be safer & more effective to treat Huntington’s disease
September 24, 2012
Major Roche-Isis deal boosts Huntington's disease gene silencing
'ASO' gene silencing drugs for HD boosted by major deal between Isis Pharmaceuticals and Roche
April 09, 2013
Gene silencing drug safe in ALS patients... bring on Huntington's disease trials
Gene silencing drug injected into spinal fluid in ALS patients proves safe. Good news for similar planned HD trials.
June 29, 2013
Liftoff: First humans treated with gene silencing drugs for HD!
Major Announcement: First HD patients treated with gene silencing drugs
October 22, 2015
You can also read About HDBuzz for information on HDBuzz or try your search on a search engine.