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Successful gene therapy trial in Parkinson’s Disease gives hope for HD

Successful gene therapy trial in Parkinson’s Disease gives hope for HD

Success for brain ‘gene therapy’ in Parkinson’s disease – good news for similar treatments being developed in HD

Dr Jeff CarrollMarch 31, 2011

The genetic 'gray area' of Huntington's disease: what does it all mean?

The genetic 'gray area' of Huntington's disease: what does it all mean?

Intermediate alleles and reduced penetrance – the genetic 'gray area' of Huntington’s disease, explained

Dr Nayana LahiriApril 22, 2011

'Floating' gene-silencing drugs into the brain with exosomes

'Floating' gene-silencing drugs into the brain with exosomes

Exosomes – tiny bubbles made by cells – could be used to get gene silencing drugs from the bloodstream into the brain

Professor Ed WildMay 19, 2011

Meet the enemy: neutron ray reveals HD protein structure

Meet the enemy: neutron ray reveals HD protein structure

Scientists use beams of neutrons to study the structure of clumps of mutant huntingtin protein

Dr Jeff CarrollMay 26, 2011

KMO inhibitor drug improves lifespan of Huntington's disease mice

KMO inhibitor drug improves lifespan of Huntington's disease mice

Positive results from tests of a new 'KMO inhibiting' drug in Huntington's disease mice

Professor Ed WildJune 02, 2011

Huntexil update: EMA asks for further trial

Huntexil update: EMA asks for further trial

European Medicines Agency (EMA) tells NeuroSearch a European license for Huntexil in HD requires another large trial

Professor Ed WildJune 06, 2011

Not all in your head: digestive problems in HD

Not all in your head: digestive problems in HD

Huntington's disease mice absorb less nutrition from food - which might help explain why human patients lose weight.

Dr Jeff CarrollJune 18, 2011

Re-routing the huntingtin protein inside cells

Re-routing the huntingtin protein inside cells

Canadian team decodes the tags that re-route the huntingtin protein within cells, helping explain how it becomes toxi

Dr Jeff CarrollJune 26, 2011

Cut-and-paste DNA: fixing mutations with 'genome editing'

Cut-and-paste DNA: fixing mutations with 'genome editing'

Scientists make precise changes to the DNA of a live animal. Could it work for human genetic diseases?

Dr Jeff CarrollJuly 18, 2011

A back-to-front hidden message in the HD gene?

A back-to-front hidden message in the HD gene?

Unzip your genes! A backwards message, hidden in the 'backup DNA' of the Huntington's disease gene... what does it me

Professor Ed WildAugust 19, 2011

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