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Huntington’s disease therapeutics conference 2023 - Day 3
Check out research updates from Day 3 of the 2022 HD Therapeutics Conference #HDTC2023
May 22, 2023
Updates from PTC Therapeutics and uniQure on their huntingtin-lowering trials
Both PTC Therapeutics and uniQure have shared updates from their respective clinical trials, testing different huntingtin-lowering approaches. We explore the data presented from both of these studies and what this means for HD family members.
June 21, 2023
Tipping the balance; new insights into HD genetic modifiers
A new study from researchers at Thomas Jefferson University delves into the details of how genetic modifiers of Huntington’s disease work.
September 01, 2023
Could halting CAG expansions be a new treatment for HD?
The gene MSH3 is getting a lot of attention in HD research lately. New findings suggest MSH3 lowering could halt CAG repeat expansions, offering a new therapeutic avenue.
October 05, 2023
Getting to the Root of Huntington's Disease: A Plant-Based Approach
Researchers used plants to study how to stop the Huntington’s disease protein from forming toxic clumps
October 15, 2023
Beyond huntingtin lowering: out-of-the-box approaches for the treatment of HD
The HD pipeline is rich and varied. Let's talk about some out-of-the-box approaches for developing drugs for HD that don't involve huntingtin lowering.
November 24, 2023
CRISPR-based drugs: one giant leap for mankind
Casgevy is the first CRISPR-based drug to make its way through the approval process, all but curing Sickle Cell Disease and it’s paving the way for similar drugs targeting other diseases. Is Huntington’s disease next?
February 14, 2024
Huntington's Disease Therapeutics Conference 2024 - Day 1
Check out research updates from Day 1 of the 2024 HD Therapeutics Conference #HDTC2024
March 05, 2024
Huntington's Disease Therapeutics Conference 2024 - Day 2
March 06, 2024
The director’s cut: how CAG repeats change the editing of genetic messages
Scientists in Massachusetts have recently advanced our understanding of how repetitive sequences in DNA can disrupt the creation and editing of genetic messenger molecules in cells, and how this could lead to the production of harmful proteins.
March 26, 2024
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