Huntington's disease therapeutics conference 2018 - day 3

Huntington's disease therapeutics conference 2018 - day 3

Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein - and lowering it

Dr Jeff CarrollMarch 02, 2018

Huntington's disease therapeutics conference 2018 - day 2

Huntington's disease therapeutics conference 2018 - day 2

DNA takes centre stage for day 2 of the Huntington's Disease Therapeutics Conference in Palm Springs

Dr Jeff CarrollMarch 01, 2018

Huntington's disease therapeutics conference 2018 - day 1

Huntington's disease therapeutics conference 2018 - day 1

Our daily roundup of the science presented at the 2018 HD Therapeutics Conference in Palm Springs

Dr Ed WildFebruary 28, 2018

An early role for the Huntington's disease gene – but don't believe all the headlines

An early role for the Huntington's disease gene – but don't believe all the headlines

A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?

Dr Jeff CarrollFebruary 27, 2018

New interest in an old target

New interest in an old target

Promising results in mice provide renewed optimism for mGluR5 antagonists

Dr Jeff CarrollJanuary 30, 2018

Ask the expert: Q&A on the huntingtin-lowering trial program

Ask the expert: Q&A on the huntingtin-lowering trial program

In a Q&A coordinated by the UK HD Association, Dr Ed Wild answers questions on the recently-announced trial

Dr Ed WildDecember 18, 2017

Success! ASO drug reduces levels of mutant protein in Huntington's disease patients

Success! ASO drug reduces levels of mutant protein in Huntington's disease patients

Amazing news from Ionis and Roche! HTTRx drug successfully lowers harmful huntingtin protein in spinal fluid

Dr Jeff CarrollDecember 11, 2017

Switch off the genome editor when you’re done

Switch off the genome editor when you’re done

CRISPR genome editing just got an off-switch. We cut through the hype to explore the technology in HD

Dr Michael FlowerNovember 02, 2017

A new way of thinking about trials to prevent Huntington's disease

A new way of thinking about trials to prevent Huntington's disease

Can we test drugs to delay or prevent the onset of Huntington's disease? New research suggests it's possible

Dr Jeff CarrollOctober 27, 2017

Update confirms Huntington's disease 'gene silencing' trial on track

Update confirms Huntington's disease 'gene silencing' trial on track

Ionis says its trial of HTTRx, intended to lower huntingtin protein, is fully recruited and plans to extend it

Dr Jeff CarrollOctober 15, 2017

New roles for huntingtin: removing a healthy protein to understand its function

New roles for huntingtin: removing a healthy protein to understand its function

Completely removing normal huntingtin in adults may disrupt healthy brain function, a recent study suggests.

Leora FoxSeptember 26, 2017