Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease

Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease

HD causes the normally helpful protein "ATM" to get a little overzealous. Now we can look for drugs to settle it down

Terry Jo BichellMarch 09, 2015

2015 Huntington's Disease Therapeutics Conference: Day 3

2015 Huntington's Disease Therapeutics Conference: Day 3

Day 3 of updates from the annual HD Therapeutics Conference in Palm Springs

Dr Jeff CarrollMarch 03, 2015

2015 Huntington's Disease Therapeutics Conference: Day 2

2015 Huntington's Disease Therapeutics Conference: Day 2

Day 2 of updates from the annual HD Therapeutics Conference in Palm Springs

Dr Jeff CarrollFebruary 26, 2015

2015 Huntington's Disease Therapeutics Conference: Day 1

2015 Huntington's Disease Therapeutics Conference: Day 1

Day 1 of updates from the annual HD Therapeutics Conference in Palm Springs

Professor Ed WildFebruary 25, 2015

Unlocking the Potential of Antibodies as a Therapy for Huntington’s Disease

Unlocking the Potential of Antibodies as a Therapy for Huntington’s Disease

Antibodies are known for their role in immunity, but researchers repurpose them in many ways. Can they be used in HD?

Lakshini MendisFebruary 18, 2015

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

HD drug changes DNA folding across generations

Melissa ChristiansonFebruary 09, 2015

mTORC1 tips the scales in Huntington’s disease mice

mTORC1 tips the scales in Huntington’s disease mice

Weighing the scales on mTORC1: A possible new target for HD therapeutics?

Joseph OchabaJanuary 27, 2015

Can this synthetic oil help feed the brain in Huntington's disease?

Can this synthetic oil help feed the brain in Huntington's disease?

A new study shows a synthetic oil called triheptanoin changes how HD brains use energy. But will it help HD?

Dr Jeff CarrollJanuary 15, 2015

Positive results announced for re-worked tetrabenazine drug in Huntington's disease

Positive results announced for re-worked tetrabenazine drug in Huntington's disease

Modified 'heavy hydrogen' form of tetrabenazine appears safe and effective for chorea in Huntington's disease

Dr Jeff CarrollDecember 22, 2014

Turning skin cells into brain cells: a Huntington's disease research breakthrough?

Turning skin cells into brain cells: a Huntington's disease research breakthrough?

Scientists can now change human skin cells into working neurons, like the ones that are most affected in HD.

Lakshini MendisNovember 27, 2014

Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

A clinical trial for an exciting therapy against HD is planned for 2015. The first step is to make sure it is safe.

Dr Leora FoxNovember 04, 2014

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