Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

HD drug changes DNA folding across generations

Melissa ChristiansonFebruary 09, 2015

mTORC1 tips the scales in Huntington’s disease mice

mTORC1 tips the scales in Huntington’s disease mice

Weighing the scales on mTORC1: A possible new target for HD therapeutics?

Joseph OchabaJanuary 27, 2015

Can this synthetic oil help feed the brain in Huntington's disease?

Can this synthetic oil help feed the brain in Huntington's disease?

A new study shows a synthetic oil called triheptanoin changes how HD brains use energy. But will it help HD?

Dr Jeff CarrollJanuary 15, 2015

Positive results announced for re-worked tetrabenazine drug in Huntington's disease

Positive results announced for re-worked tetrabenazine drug in Huntington's disease

Modified 'heavy hydrogen' form of tetrabenazine appears safe and effective for chorea in Huntington's disease

Dr Jeff CarrollDecember 22, 2014

Turning skin cells into brain cells: a Huntington's disease research breakthrough?

Turning skin cells into brain cells: a Huntington's disease research breakthrough?

Scientists can now change human skin cells into working neurons, like the ones that are most affected in HD.

Lakshini MendisNovember 27, 2014

Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

A clinical trial for an exciting therapy against HD is planned for 2015. The first step is to make sure it is safe.

Dr Leora FoxNovember 04, 2014

Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis

Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis

CREST-E, a trial of the supplement creatine, has been stopped after an early analysis found it couldn't show benefit

Professor Ed WildOctober 29, 2014

Should we worry about a huntingtin invasion?

Should we worry about a huntingtin invasion?

Cool lab experiments show the huntington's disease protein jumping between cells. Does this matter for HD patients?

Dr Jeff CarrollOctober 27, 2014

EuroBuzz 2014 Video, day one

EuroBuzz 2014 Video, day one

Video of our first live session at the European Huntington's Disease Network Meeting.

Professor Ed WildOctober 10, 2014

EuroBuzz 2014 Video, day two

EuroBuzz 2014 Video, day two

Video of our second live session at the European Huntington's Disease Network Meeting.

Dr Jeff CarrollOctober 10, 2014

Melatonin alterations in Huntington's disease help explain trouble with sleep

Melatonin alterations in Huntington's disease help explain trouble with sleep

Study shows HD patients have decreased levels of melatonin, which may explain why so many suffer from sleep problems

Dr Leora FoxOctober 07, 2014