Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

A clinical trial for an exciting therapy against HD is planned for 2015. The first step is to make sure it is safe.

Dr Leora FoxNovember 04, 2014

Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis

Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis

CREST-E, a trial of the supplement creatine, has been stopped after an early analysis found it couldn't show benefit

Professor Ed WildOctober 29, 2014

Should we worry about a huntingtin invasion?

Should we worry about a huntingtin invasion?

Cool lab experiments show the huntington's disease protein jumping between cells. Does this matter for HD patients?

Dr Jeff CarrollOctober 27, 2014

EuroBuzz 2014 Video, day one

EuroBuzz 2014 Video, day one

Video of our first live session at the European Huntington's Disease Network Meeting.

Professor Ed WildOctober 10, 2014

EuroBuzz 2014 Video, day two

EuroBuzz 2014 Video, day two

Video of our second live session at the European Huntington's Disease Network Meeting.

Dr Jeff CarrollOctober 10, 2014

Melatonin alterations in Huntington's disease help explain trouble with sleep

Melatonin alterations in Huntington's disease help explain trouble with sleep

Study shows HD patients have decreased levels of melatonin, which may explain why so many suffer from sleep problems

Dr Leora FoxOctober 07, 2014

EuroBuzz 2014: day three

EuroBuzz 2014: day three

Our third and final report on the 2014 European Huntington's Disease Network meeting in Barcelona

Professor Ed WildSeptember 21, 2014

EuroBuzz 2014: day two

EuroBuzz 2014: day two

HDBuzz reports on the second day of science at the European HD Network meeting in Barcelona

Dr Jeff CarrollSeptember 20, 2014

EuroBuzz 2014: day one

EuroBuzz 2014: day one

Highlights from the opening day of the 2014 European Huntington's Disease network in Barcelona, Spain

Professor Ed WildSeptember 19, 2014

Going toe-to-toe with tau: new insights into the chemical basis of Huntington’s disease

Going toe-to-toe with tau: new insights into the chemical basis of Huntington’s disease

Does tau protein – which causes problems in other neurodegenerative diseases – contribute to Huntington's disease?

Siddharth NathSeptember 13, 2014

New results bring BDNF therapies into focus

New results bring BDNF therapies into focus

Some unexpected findings suggest new ways to aim at an old target in HD

Dr Jeff CarrollAugust 18, 2014

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