Enemy at the gates – huntingtin disrupts nuclear transport

Enemy at the gates – huntingtin disrupts nuclear transport

Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.

Tom PeskettApril 21, 2017

FDA approves a new drug for symptoms of Huntington's disease

FDA approves a new drug for symptoms of Huntington's disease

Deutetrabenazine becomes the first new drug in a decade licensed by the FDA for symptoms of Huntington's disease

Dr Jeff CarrollApril 05, 2017

Sheep leading the flock: metabolism and biomarkers in HD

Sheep leading the flock: metabolism and biomarkers in HD

Sheep can help us to identify HD biomarkers and recognize metabolic changes that occur before symptoms develop.

Leora FoxMarch 27, 2017

Weeding out the truth: can cannabis improve Huntington’s?

Weeding out the truth: can cannabis improve Huntington’s?

What can individual experiences with cannabis tell us about Huntington's disease?

Dr Michael FlowerFebruary 24, 2017

Huntingtin grabs a hammer: DNA repair in HD

Huntingtin grabs a hammer: DNA repair in HD

Huntingtin helps fix damaged DNA, a recent study suggests, under the direction of a gene repair protein called ATM.

Leora FoxFebruary 22, 2017

The benefits of migration, highlighted in Huntington's disease

The benefits of migration, highlighted in Huntington's disease

Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again

Dr Michael FlowerFebruary 10, 2017

Treasure your exceptions - using outliers to understand Huntington's disease onset and progression

Treasure your exceptions - using outliers to understand Huntington's disease onset and progression

A new study provides the framework for finding factors that affect the onset and progression of HD

Mr. Shawn MinnigJanuary 12, 2017

A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?

A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?

What if some problems in HD were due to something other than a harmful protein?

Dr Jeff CarrollDecember 30, 2016

Pfizer Amaryllis trial ends in disappointment: no improvement in Huntington's disease symptoms

Pfizer Amaryllis trial ends in disappointment: no improvement in Huntington's disease symptoms

Pfizer announces the 'Amaryllis' trial of a PDE-10 inhibitor drug failed to improve symptoms of HD

Dr Ed WildDecember 16, 2016

Important advances in next generation genome editing tools for Huntington's Disease

Important advances in next generation genome editing tools for Huntington's Disease

Work with genome editing techniques (zinc fingers and CRISPR) brings these tools closer to use in HD clinical trials

Mr. Shawn MinnigOctober 31, 2016

Sorry folks, the PRIDE-HD trial did NOT show that Pridopidine slows the progression of Huntington's disease

Sorry folks, the PRIDE-HD trial did NOT show that Pridopidine slows the progression of Huntington's disease

HDBuzz helps untangle some bold claims about the just-announced results of the PRIDE-HD trial of pridopidine in HD

Dr Jeff CarrollSeptember 30, 2016