Treasure your exceptions - using outliers to understand Huntington's disease onset and progression

Treasure your exceptions - using outliers to understand Huntington's disease onset and progression

A new study provides the framework for finding factors that affect the onset and progression of HD

Mr. Shawn MinnigJanuary 12, 2017

A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?

A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?

What if some problems in HD were due to something other than a harmful protein?

Dr Jeff CarrollDecember 30, 2016

Pfizer Amaryllis trial ends in disappointment: no improvement in Huntington's disease symptoms

Pfizer Amaryllis trial ends in disappointment: no improvement in Huntington's disease symptoms

Pfizer announces the 'Amaryllis' trial of a PDE-10 inhibitor drug failed to improve symptoms of HD

Dr Ed WildDecember 16, 2016

Important advances in next generation genome editing tools for Huntington's Disease

Important advances in next generation genome editing tools for Huntington's Disease

Work with genome editing techniques (zinc fingers and CRISPR) brings these tools closer to use in HD clinical trials

Mr. Shawn MinnigOctober 31, 2016

Sorry folks, the PRIDE-HD trial did NOT show that Pridopidine slows the progression of Huntington's disease

Sorry folks, the PRIDE-HD trial did NOT show that Pridopidine slows the progression of Huntington's disease

HDBuzz helps untangle some bold claims about the just-announced results of the PRIDE-HD trial of pridopidine in HD

Dr Jeff CarrollSeptember 30, 2016

EuroBuzz 2016: The Euro-HD Network Meeting in The Hague

EuroBuzz 2016: The Euro-HD Network Meeting in The Hague

All our tweets from #EHDN2016 in one mega-article

Dr Jeff CarrollSeptember 23, 2016

Ultra-rare mutations highlight the importance of the HD gene in brain development

Ultra-rare mutations highlight the importance of the HD gene in brain development

New technology enables researchers to find ultra-rare mutations in the HD gene, distinct from the one causing HD

Megan KrenchAugust 29, 2016

Deutetrabenazine for Huntington's disease: a positive trial but the FDA says no? Not exactly...

Deutetrabenazine for Huntington's disease: a positive trial but the FDA says no? Not exactly...

A new scientific paper & lots of headlines about deutetrabenazine, a twist on treating chorea in Huntington's disease

Dr Peter McColganAugust 17, 2016

A support system gone wrong - glial cells contribute to HD symptoms

A support system gone wrong - glial cells contribute to HD symptoms

An elegant new study helps determine how much brain cells called glia matter to HD symptoms

Dr Jackie JohnsonAugust 02, 2016

Slightly long CAG repeats are more common than we thought

Slightly long CAG repeats are more common than we thought

A new population study reveals that relatively mild forms of the HD mutation are much more common than we thought

Dr Jeff CarrollJuly 05, 2016

Early exposure to the HD protein may cause life-long symptoms

Early exposure to the HD protein may cause life-long symptoms

A surprising new mouse study suggests the mutant HD gene may do some of its damage during embryonic development

Mr. Shawn MinnigJune 28, 2016