Articles with the topic: DNA repair

When interrupting is good: genetic hiccups that protect against Huntington's disease

When interrupting is good: genetic hiccups that protect against Huntington's disease

Multiple teams find small differences in the 'CAG repeat' bit of the Huntington's disease gene. They don't directly change the huntingtin protein, but do alter the age of symptom onset. What's behind this enigma and what does it mean for patients?

Dr Jeff CarrollMarch 14, 2019

Huntington's disease therapeutics conference 2018 - day 2

Huntington's disease therapeutics conference 2018 - day 2

DNA takes centre stage for day 2 of the Huntington's Disease Therapeutics Conference in Palm Springs

Dr Jeff CarrollMarch 01, 2018

An early role for the Huntington's disease gene – but don't believe all the headlines

An early role for the Huntington's disease gene – but don't believe all the headlines

A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?

Dr Jeff CarrollFebruary 27, 2018

Enemy at the gates – huntingtin disrupts nuclear transport

Enemy at the gates – huntingtin disrupts nuclear transport

Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.

Tom PeskettApril 21, 2017

Huntingtin grabs a hammer: DNA repair in HD

Huntingtin grabs a hammer: DNA repair in HD

Huntingtin helps fix damaged DNA, a recent study suggests, under the direction of a gene repair protein called ATM.

Leora FoxFebruary 22, 2017