Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.

Are you looking for our logo? You can download our logo and get information about how to use it on our sharing page

Articles with the topic: huntingtin-structure

The structure of the protein that causes Huntington's disease, revealed

The structure of the protein that causes Huntington's disease, revealed

Caroline Casey on April 03, 2018

The cause of Huntington’s disease has been known since 1993, but the physical structure of the healthy huntingtin protein proved difficult to discover until now. German scientists have now revealed the shape of the huntingtin protein for the first time. Although the structure of the mutant form of the protein was not investigated, this study provides an excellent platform to build upon and will boost drug development efforts.

Electron beam snaps best images yet of Huntington's disease protein

Electron beam snaps best images yet of Huntington's disease protein

Tom Peskett on June 21, 2016

Figuring out the shape of a protein can help scientists understand how it works and what goes wrong in disease. Huntingtin, the protein that causes Huntington's disease, has been an elusive target. A recent study using electron microscopes offers a striking glimpse of huntingtin, paving the way for future work.