Articles with the topic: gene-editing

Interruptions are encouraged

Interruptions are encouraged

A CRISPR-based approach called “base editing” is being explored to develop a new potential treatment for Huntington's disease. Editing a single letter in the genetic code with base editing may be the key for delaying HD symptoms, maybe by a decade.

Dr Chris KayOctober 14, 2024

CRISPR-based drugs: one giant leap for mankind

CRISPR-based drugs: one giant leap for mankind

Casgevy is the first CRISPR-based drug to make its way through the approval process, all but curing Sickle Cell Disease and it’s paving the way for similar drugs targeting other diseases. Is Huntington’s disease next?

Dr Sarah HernandezFebruary 14, 2024

Another tool in the box: Creation of a molecular “dimmer switch” advances gene editing

Another tool in the box: Creation of a molecular “dimmer switch” advances gene editing

A new system has been developed that allows researchers to fine-tune gene expression with oral drugs, work that provides a powerful tool for gene editing.

Dr Leora FoxAugust 30, 2021

A first for CRISPR gene editing could have wider applications for human disease

A first for CRISPR gene editing could have wider applications for human disease

A successful early trial of a drug for Familial Transthyretic Amyloidosis showed that CRISPR gene editing could be safely used in the human body. What does this mean for gene editing in HD?

Daniel O’ReillyJuly 21, 2021

Caution urged for the use of gene-editing technology CRISPR

Caution urged for the use of gene-editing technology CRISPR

A recent series of studies on the gene-editing method CRISPR have raised concerns about the suitability of this technology for the treatment of genetic illnesses such as Huntington's disease

Dr Rachel HardingAugust 12, 2020

New molecule can reverse the Huntington's disease mutation in lab models

New molecule can reverse the Huntington's disease mutation in lab models

A collaborative team of scientists from Canada and Japan have identified a small molecule which can change the CAG-repeat length in different lab models of Huntington's disease. #HuntingtonsDisease #DrugDiscovery

Dr Michael FlowerApril 06, 2020

Screening the entire genome for new drug targets for HD

Screening the entire genome for new drug targets for HD

Scientists screen the ENTIRE genome to find new potential therapeutic targets for HD. This ambitious study provides a wealth of data for HD researchers

Dr Rachel HardingFebruary 23, 2020

First Dolly, now Piglet; a new Huntington’s disease pig knock-in model confirmed

First Dolly, now Piglet; a new Huntington’s disease pig knock-in model confirmed

For the first time in HD research, an animal model has been created in pigs using 2 cutting edge DNA editing t

Caroline CaseyJuly 10, 2018

An early role for the Huntington's disease gene – but don't believe all the headlines

An early role for the Huntington's disease gene – but don't believe all the headlines

A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?

Dr Jeff CarrollFebruary 27, 2018

Donate

Please consider making a donation if you value the services that HDBuzz provides. We want HDBuzz to be sustainable so that we can continue to report unbiased science to the HD community.

With your support, we can ensure the continuity of our services. Nothing is expected, but everything is appreciated and sustains what we do at HDBuzz. Please consider giving what you're able. More information...