Articles with the topic: anti-sense

Advances on many fronts in the battle against the protein that causes Huntington's disease

Advances on many fronts in the battle against the protein that causes Huntington's disease

This fall sees exciting announcements from a number of companies focused on novel Huntingtin Lowering technologies, including Wave, PTC and Voyager

Dr Jeff CarrollDecember 04, 2018

Kids sometimes get Huntington’s disease too

Kids sometimes get Huntington’s disease too

Finally, a big study that shows what childhood HD looks like. This will help us work out if new drugs work in children too

Dr Michael FlowerOctober 10, 2018

Important advances in next generation genome editing tools for Huntington's Disease

Important advances in next generation genome editing tools for Huntington's Disease

Work with genome editing techniques (zinc fingers and CRISPR) brings these tools closer to use in HD clinical trials

Mr. Shawn MinnigOctober 31, 2016

How NOT to write a news article about a clinical trial

How NOT to write a news article about a clinical trial

A confusing story about a huntingtin lowering trial is published in the Telegraph, but cool new stuff is happening!

Dr Jeff CarrollMarch 11, 2016

Liftoff: First humans treated with gene silencing drugs for HD!

Liftoff: First humans treated with gene silencing drugs for HD!

Major Announcement: First HD patients treated with gene silencing drugs

Dr Jeff CarrollOctober 22, 2015

New tool to measure outcomes in Huntington’s Disease clinical trials

New tool to measure outcomes in Huntington’s Disease clinical trials

A better tool for HD trials! New research shows innovative way to measure mutant Huntingtin outside the brain

Megan KrenchSeptember 03, 2015

Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

A clinical trial for an exciting therapy against HD is planned for 2015. The first step is to make sure it is safe.

Leora FoxNovember 04, 2014

Could a 'brain shuttle' get Huntington's disease drugs to where they're needed?

Could a 'brain shuttle' get Huntington's disease drugs to where they're needed?

Roche's 'brain shuttle' sneaks drugs past the blood-brain barrier. Could it work for HD gene silencing drugs?

Dr Jeff CarrollJanuary 20, 2014

A back-to-front hidden message in the HD gene?

A back-to-front hidden message in the HD gene?

Unzip your genes! A backwards message, hidden in the 'backup DNA' of the Huntington's disease gene... what does it me

Dr Ed WildAugust 19, 2011