Articles with the topic: genetics

When interrupting is good: genetic hiccups that protect against Huntington's disease

When interrupting is good: genetic hiccups that protect against Huntington's disease

Multiple teams find small differences in the 'CAG repeat' bit of the Huntington's disease gene. They don't directly change the huntingtin protein, but do alter the age of symptom onset. What's behind this enigma and what does it mean for patients?

Dr Jeff CarrollMarch 14, 2019

Huntington's disease therapeutics conference 2019 - Day 3

Huntington's disease therapeutics conference 2019 - Day 3

New insights into the huntingtin protein, and further progress in turning genetic quirks that modify the course of HD into treatments, on the final day of the therapeutics conference

Joel Stanton and Dr Jeff CarrollMarch 05, 2019

Kids sometimes get Huntington’s disease too

Kids sometimes get Huntington’s disease too

Finally, a big study that shows what childhood HD looks like. This will help us work out if new drugs work in children too

Dr Michael FlowerOctober 10, 2018

Huntington's Disease Therapeutics Conference 2017 - Day 1

Huntington's Disease Therapeutics Conference 2017 - Day 1

HDBuzz summarises all the science from the 2017 Huntington's Disease Therapeutics Conference in Malta - day 1

Dr Jeff CarrollApril 27, 2017

Ultra-rare mutations highlight the importance of the HD gene in brain development

Ultra-rare mutations highlight the importance of the HD gene in brain development

New technology enables researchers to find ultra-rare mutations in the HD gene, distinct from the one causing HD

Megan KrenchAugust 29, 2016

Slightly long CAG repeats are more common than we thought

Slightly long CAG repeats are more common than we thought

A new population study reveals that relatively mild forms of the HD mutation are much more common than we thought

Dr Jeff CarrollJuly 05, 2016

Important drug targets yielded by new genetic study of HD

Important drug targets yielded by new genetic study of HD

A genetic study confirms that minute differences in DNA repair genes can influence the age of HD symptom onset.

Leora FoxMay 02, 2016

Huntington's Disease Therapeutics Conference 2016 - day 1

Huntington's Disease Therapeutics Conference 2016 - day 1

Proteins and DNA - Jeff and Ed report from day 1 of the 2016 #huntingtonsdisease therapeutics conference

Dr Ed WildFebruary 25, 2016

Huge study reveals new 'genetic modifiers' of Huntington's disease

Huge study reveals new 'genetic modifiers' of Huntington's disease

GeM-HD identifies the first solid leads in the hunt for genetic variations that affect Huntington's disease onset

Dr Jeff CarrollJuly 31, 2015