Multiple teams find small differences in the 'CAG repeat' bit of the Huntington's disease gene. They don't directly change the huntingtin protein, but do alter the age of symptom onset. What's behind this enigma and what does it mean for patients?
New insights into the huntingtin protein, and further progress in turning genetic quirks that modify the course of HD into treatments, on the final day of the therapeutics conference
Finally, a big study that shows what childhood HD looks like. This will help us work out if new drugs work in children too
HDBuzz summarises all the science from the 2017 Huntington's Disease Therapeutics Conference in Malta - day 1
New technology enables researchers to find ultra-rare mutations in the HD gene, distinct from the one causing HD
A new population study reveals that relatively mild forms of the HD mutation are much more common than we thought
A genetic study confirms that minute differences in DNA repair genes can influence the age of HD symptom onset.
Proteins and DNA - Jeff and Ed report from day 1 of the 2016 #huntingtonsdisease therapeutics conference
GeM-HD identifies the first solid leads in the hunt for genetic variations that affect Huntington's disease onset