Articles with the topic: drug-development

Liftoff: First humans treated with gene silencing drugs for HD!

Major Announcement: First HD patients treated with gene silencing drugs

Dr Jeff Carroll | October 22, 2015

New tool to measure outcomes in Huntington’s Disease clinical trials

A better tool for HD trials! New research shows innovative way to measure mutant Huntingtin outside the brain

Megan Krench | September 03, 2015

2015 Huntington's Disease Therapeutics Conference: Day 2

Day 2 of updates from the annual HD Therapeutics Conference in Palm Springs

Dr Jeff Carroll | February 26, 2015

2015 Huntington's Disease Therapeutics Conference: Day 1

Day 1 of updates from the annual HD Therapeutics Conference in Palm Springs

Professor Ed Wild | February 25, 2015

Drug Improves Huntington’s Symptoms in Mice – and Their Offspring

HD drug changes DNA folding across generations

Melissa Christianson | February 09, 2015

mTORC1 tips the scales in Huntington’s disease mice

Weighing the scales on mTORC1: A possible new target for HD therapeutics?

Joseph Ochaba | January 27, 2015

Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

A clinical trial for an exciting therapy against HD is planned for 2015. The first step is to make sure it is safe.

Dr Leora Fox | November 04, 2014

2CARE study of coenzyme Q for Huntington's disease ends in disappointment

The largest ever HD drug trial, testing coenzyme Q10, is halted for 'futility'. What does that mean for HD research?

Dr Jeff Carroll | August 13, 2014

Could HD be caused by amino acid deficiency?

Does a specific amino acid deficiency contribute to the development of HD?