CAG repeats expand in some parts of the body and brain as people with HD get older, a phenomenon known as somatic instability. Learn more about how researchers are exploring somatic instability and DNA repair to design therapies for HD.
We know that HD-related changes can occur many years before symptom onset, but how early do those changes begin? A team of researchers set out to determine that with a new comprehensive study in pre-manifest HD young adults.
As promised, HDBuzz's Jeff Carroll finally signed up for the Enroll-HD study. Learn more about this important global HD "observational study" here.
Can we test drugs to delay or prevent the onset of Huntington's disease? New research suggests it's possible
HDBuzz summarizes the science from an unusually large and energized @HDSA convention in Baltimore
Companions of HD gene carriers are more likely to notice psychological changes in presymptomatic HD.
A better tool for HD trials! New research shows innovative way to measure mutant Huntingtin outside the brain
Does an ‘intermediate’ CAG repeat count in the Huntington’s disease gene cause brain changes?
Final results from the TRACK-HD study show very specific changes in HD. We're ready for trials: bring on the drugs!