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Double success for huntingtin RNAi gene silencing

2 bits of good news for RNAi gene silencing in HD: it's safe over six months, and a way to treat bigger brain areas
January 24, 2012
Could mesenchymal stem cells deliver gene silencing drugs?

Stem cells can deliver HD gene silencing drugs into cells in a dish. Do we need another delivery technology?
January 31, 2012
ASO gene silencing reaches further, lasts longer

Silencing the Huntingtin gene using ASO drugs reaches further, lasts longer and is safe. Human trial soon?
June 21, 2012
Shooting the messenger with single-stranded RNA gene silencing

New ‘single-stranded RNA’ gene silencing drugs could be safer & more effective to treat Huntington’s disease
September 24, 2012
Major Roche-Isis deal boosts Huntington's disease gene silencing

'ASO' gene silencing drugs for HD boosted by major deal between Isis Pharmaceuticals and Roche
April 09, 2013
Gene silencing drug safe in ALS patients... bring on Huntington's disease trials

Gene silencing drug injected into spinal fluid in ALS patients proves safe. Good news for similar planned HD trials.
June 29, 2013
Liftoff: First humans treated with gene silencing drugs for HD!

Major Announcement: First HD patients treated with gene silencing drugs
October 22, 2015
Update confirms Huntington's disease 'gene silencing' trial on track

Ionis says its trial of HTTRx, intended to lower huntingtin protein, is fully recruited and plans to extend it
October 15, 2017
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